How much does the administration of antacids and other alkaline substances effect Adderalls Bioavailability and half life? Same question with acidic substances (Ie Citric Acid, Phosphoric Acid) and how does daily consumption effect Bioavailability and Half life?


Urinary and stomach pH levels can have the strongest effect on DL-amphetamine excretion and absorption. Co-administration of acidic substances (e.g. citric acid) causes an accelerated excretion of DL-amphetamine while co-administration of alkaline agents (e.g. antacids) causes a marked increase in both retention and absorption of amphetamines potentially resulting in dangerously high serum amphetamine levels.

^ From the wiki

Pretty sure this only applies to taking it orally...just rail it