What does everyone think about the governments sheduling of Salvia that is soon going to happen?

Ive always been interested in salvia. It hasn't been till recently that they found out how it worked, summer 2002 I believe. It is also almost impossible to synthesize salvinorin A (the active constituent in salvia, salvinorin B was found innefective (or weak). I saw one synthesis on Rhodium that was theoretical.

Just wondering what you think about the possible ban and if anyone has tried the drug and has liked it or not.

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Ive always been interested in salvia. It hasn't been till recently that they found out how it worked, summer 2002 I believe.

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did they? i'd like to read an article if you can find one.

it's a drug, it brings people chemical pleasure, the big Gov. don't like [the] people enjoying themselves, [and that is the] end of that.

[for the people, by the people, fuck the people]

Do you have references for this alleged ban? Not that I don't beleive you, I'm just sceptical.

(displayed on the first page of searches for "US+ban+salvia")

Salvia Divinorum Legal Status Information

I don't got time right now to find the paper on how it works (I have a hard time understanding it, it's so technical). But I got to get out of the city and go all the way to the country for thanksgiving. Anyway the paper said the main site of action found for salvinorin a is at the kappa opiod receptor. Im not sure but I think they also said that is a receptor sit or something that is responsible for some of the actions of mental diseases such as schizophrenia, but I realy don't remember. I'll try to find the paper when I get back.

Damn. I read the report and it was quite disappointing. Didn't see anything in it about good old Canada though.

"What? The land of the free?
Whoever told you that is your enemy!"
- Zach de la Rocha - Rage Against The Machine

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I'll try to find the paper when I get back.

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i'm looking forward to it, thanks.

It's on Erowid under: salvia/ selective opioid agonist. It's been there for a while.

Salvia is an opioid receptor agonist like the drug Enadoline. (enadoline research was discontinued because of its strange hallucinogenic properties). Like enadoline, salvia may be helpful to recovering heroin addicts.

And yes, there is a bill in the works to schedule salvia.

I have a bunch of dried salvia leaves, how can i extract the shti to trip with easy?

So buy it whilst ye kin.

Easy is dead. You can't trip with him.

Heres the paper, its from http://www.sagewisdom.org/
The Salvia divinorum Research and
Information Center
and the paper is on PNAS

Salvinorin A: A potent naturally occurring nonnitrogenous opioid selective agonist
Bryan L. Roth*,,,�,�, Karen Baner*, Richard Westkaemper, Daniel Siebert**, Kenner C. Rice, SeAnna Steinberg*, Paul Ernsberger*,, and Richard B. Rothman��
* National Institute of Mental Health Psychoactive Drug Screening Program, and Departments of Biochemistry, Psychiatry, � Neurosciences, and Pharmacology and Nutrition, Case Western Reserve University Medical School, Cleveland, OH 44106; �� Clinical Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224; Department of Medicinal Chemistry, Medical College of Virginia, Richmond, VA 23298; ** The Salvia divinorum Research and Information Center, Malibu, CA 90263; and Laboratory of Medicinal Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892

Edited by Erminio Costa, University of Illinois, Chicago, IL, and approved July 9, 2002 (received for review April 18, 2002)

Salvia divinorum, whose main active ingredient is the neoclerodane diterpene Salvinorin A, is a hallucinogenic plant in the mint family that has been used in traditional spiritual practices for its psychoactive properties by the Mazatecs of Oaxaca, Mexico. More recently, S. divinorum extracts and Salvinorin A have become more widely used in the U.S. as legal hallucinogens. We discovered that Salvinorin A potently and selectively inhibited 3H-bremazocine binding to cloned opioid receptors. Salvinorin A had no significant activity against a battery of 50 receptors, transporters, and ion channels and showed a distinctive profile compared with the prototypic hallucinogen lysergic acid diethylamide. Functional studies demonstrated that Salvinorin A is a potent opioid agonist at cloned opioid receptors expressed in human embryonic kidney-293 cells and at native opioid receptors expressed in guinea pig brain. Importantly, Salvinorin A had no actions at the 5-HT2A serotonin receptor, the principal molecular target responsible for the actions of classical hallucinogens. Salvinorin A thus represents, to our knowledge, the first naturally occurring nonnitrogenous opioid-receptor subtype-selective agonist. Because Salvinorin A is a psychotomimetic selective for opioid receptors, opioid-selective antagonists may represent novel psychotherapeutic compounds for diseases manifested by perceptual distortions (e.g., schizophrenia, dementia, and bipolar disorders). Additionally, these results suggest that opioid receptors play a prominent role in the modulation of human perception.


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� To whom reprint requests should be addressed. E-mail: roth@biocserver.cwru.edu.
www.pnas.org/cgi/doi/10.1073/pnas.182234399

Erowid has information on extractions http://www.erowid.org/plants/salvia/salvia.shtml

scroll down and there should be three different ways to extract it.