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Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, making beer, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference.

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 #1 
Old 2001-05-08, 16:02
L-i-q-u-i-d L-i-q-u-i-d is offline
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Default Amitriptyline

Hey just wanderin do any of yall know if 10 and 20mg amitriptyline prescribed for sleep, could serve as any thing other. if so dosage and affects; reason why
 #2 
Old 2001-05-08, 16:13
sckbch sckbch is offline
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Default Re: Amitriptyline

AMITRIPTYLINE
0.0 OVERVIEW
A. AMITRIPTYLINE is a tricyclic antidepressant.
B. DOSING INFORMATION: Initial oral doses are 75 to 100 mg/day as a single dose or in divided doses, with increases to 200 to 300 mg/day; intramuscular doses are 80 to 120 mg/day in 4 divided doses; geriatric patients should receive reduced doses; adolescent oral doses are 1 to 1.5 mg/kg/day in 3 divided doses.
C. PHARMACOKINETICS: Therapeutic effects begin in 7 to 21 days; peak serum levels occur within 4 h and protein binding is 90% to 95%; elimination half-life is 9 to 25 h, with an average of 15 h; hepatic metabolism to NORTRIPTYLINE (active), 10-hydroxy derivatives, and conjugated derivatives is followed with renal excretion of approximately 18% as unchanged drug.
D. CAUTIONS: Adverse effects include aplastic anemia, leukopenia, pancytopenia, purpura, thrombocytopenia, electrocardiogram changes, heart block, ventricular tachycardia, ventricular extrasystoles, cardiomyopathy, hypotension, malignant hypertension, aggression, confusion, agitation, disorientation, seizures, dyskinesias, sedation, delirium, psychomotor impairment, paresthesias, mania, myoclonus, galactorrhea, inappropriate ADH secretion, weight gain, hypoglycemia, porphyria, hyperthermia, dry mouth, stomatitis, paralytic ileus, constipation, abdominal distention, gastroesophageal reflux, impotence, sexual dysfunction, hepatotoxicity, ophthalmoplegia, phototoxicity, myasthenia gravis, and withdrawal symptoms.
E. CLINICAL APPLICATIONS: AMITRIPTYLINE is an effective antidepressant for the treatment of major depressive disorders. The drug has also been used for postherpetic neuralgia, chronic pain, panic attacks, and agitation. The drug has been favorably compared to many of the tricyclic antidepressants, FLUOXETINE, and TRAZODONE.
 #3 
Old 2001-05-08, 21:59
dankgirl420 dankgirl420 is offline
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Default Re: Amitriptyline

Also, it is used in the prevention of cluster migraines and the treatment of pathologic weeping and laughing due to multiple sclerosis.

It's sedative effects can help when depression is associated with anxiety and sleep disturbance.
 #4 
Old 2001-05-09, 09:06
slpwlkr333 slpwlkr333 is offline
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Default Re: Amitriptyline

eh, pathalogical laughing- i fuckin hate those people- my friends step father has a disorder from nam and has that shit. Nutty as motherfucker, makes me wanna fuckin stab him. STOP LAUGHING. AHHHH.


Tricyclics are pretty crazy so becareful- normally get other scripts with them for fight of side effects( i.e. cogentin(benztropine)) which has EXTREME, but also extremely dangerous recreational value. the drugs used to counter side effects and tricyclics are all pretty unsafe and a normal dose of cogentin and doxepin which wasnt very high at all i was prescribed to in 9th grade put me into a coma, for real( i was doing any drugs or taking more than my prescribed dose)
 #5 
Old 2001-05-09, 17:02
L-i-q-u-i-d L-i-q-u-i-d is offline
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Default Re: Amitriptyline

Damn man I thought they were Fuckin sleepin pills; maybe i just got my scripts confused Ive had bout fuckin 20 in the last year and 1/2
 #6 
Old 2001-05-09, 21:42
dankgirl420 dankgirl420 is offline
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Default Re: Amitriptyline

A doctor can prescribe them to you if you have sleeping problems. That is one if its indications. Especially, if you can't sleep due to anxiety.
 #7 
Old 2001-05-09, 23:15
slpwlkr333 slpwlkr333 is offline
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Default Re: Amitriptyline

most(if not all) tricyclics make most people tired or at least lethargic as balls dood. like a non- cool version of ativan, basically a pill that gives you everything you dont want from benzos, pills containing benzo side effects mostly only.
 
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