Is there anything stopping me from wiring several resistors in series to get my target resistance over just getting the equivalent resistor? I'm wondering because i have a bunch of random resistors but no single resistor with the resistance I need and I would rather not buy a 50 pack of the same resistors I would unlikely need again (and no, electronic stores near me do not have that resistor I need either).

As long as you don't exceed the power rating of the lowest rated resistor, you will be ok.