I was just wondering on which drugs I should not mix? Common sense says don't mix uppers with downers; however, I hear people say all the time the pop benzos to get some sleep while they're coming down from speed. My only knowledge is not to mix uppers with opiates.

What drugs should not be mixed?

Don't mix large amounts of heavy downers(benzos, alcohol, opiates). That's all I've got.

speedballs are great if your body can handle that sort of thing. anyways from personal real life experience---

don't mix excessive amounts of xanax/valium with heroin. easiest way to flop out.

Don't mix uppers with uppers or downers with downers.

Uppers+uppers=heart attack

Downers+downers=go to sleep and never wake up again

i think mixing alot of uppers with downers can be bad..

One time i was at a rich kid party in orange county. they had hundreds of redbulls and lots of vodka. Thats all i drank thatwhole night, i kept waking up shaking with my heart mixing from slow to fast.

the hangover was pretty shitty too

WOuld It be okay to mix (5/325) oxycodone with (5/500) Hydrocodone? both opiates so.. idk I didnt want to open another thread just to ask soo....?

Both are painkillers. You will be fine. Blow the oxy and parachute the hydro , proceed to nod.

parachute/eat the hydro, IV the oxy.

opiates are fine to mix so long as its no in excess. best combo ever is high quality heroin and oxymorph hands down.

Both are painkillers. You will be fine. Blow the oxy and parachute the hydro , proceed to nod.

thanks dude fer the quick answer.. Done, and done. I think im good to go boardin now

well, personally i can't mix gabapentin with weed or i vomit. Also, don't drink and drop RC's, more vomiting will ensue.

What drugs should not be mixed?

PCP w/ alcohol or benzos, or all 3 together

Your bound to end up in central

kinda random, but...

rimonabant + weed = ftl

no shit.

big 2nd on this, the only time where i was ever close to dying was off of 8 mg of klonopin, and a couple of ten bags of tar iv'd.

waking up in an ambulance FTL

uppers and downers makes you want to take more of both, i remember the first time i mixed a cap of h with some coke, daaamn it was fun. and coke + alcohol isnt all too bad either, with that little extra oomph from the coke.

SSRI's and E dont mix well at all (serotonin syndrome)

MAOI's and alot of things



but for the most part, in moderation, most combinations can be pretty fun. i do like mixing opiates and benzos in moderation, i was just in a stupid klonopin state when i od'ed. would have been fine with 1/4 of the klonopin dose with the H. but alas, you can always take more drugs over time if they're not affecting you, and never take less once they've been taken, if you know what i mean.

Both are painkillers. You will be fine. Blow the oxy and parachute the hydro , proceed to nod.

do not snort APAP. CWE if you want to snort of IV.

Dont mix MAOIs (non recreational) with ANY drugs.

Dont Mix SSRIs with any drug that affects serotonin.

Dont mix benzos with opiates. This has killed many totseans.

Don't mix sodium thiopental, pancuronium, and potassium chloride.

There's a lot of like specific drugs that you can't mix together, it's not really general like you can't mix uppers with downers (even though I'm sure that CAN'T be good for your body, but whatever). But just one that I can remember right now is mixing tramadol with coke can result in a seizure or worse. Then I've heard of people having a seizure from mixing acid and coke. I'd just say, unless you already know that you can mix together whatever you're taking, look it up.

Oh yea, another thing that you gotta be careful with is mixing downers together. Like alcohol and opiates, or opiates and benzos, or all three together. Oh, and I think I also heard that it's a bad idea to mix stimulants with DXM.

crack and meth