Why do opiates get harder to quit as your dose gets lower?
The title probably makes me look like an idiot... I know that if your taking say, 10 units [of whatever] a day and you cut it to 2 immediately, your not gonna be a happy camper. What I'm talking about is if your taking 10 units a day, and you reduce it by small amounts each day, why it gets harder as you approach zero.
In the back of my head I always thought it nonsense and not possible, but I went n' got myself addicted to opium 'tea' over the last few months. It's not severe and doesn't compare to quitting oxycodone, but it is there. I tried just dropping it on a moments notice a month or so back, and it kept me up almost 2 straight nights tossing and turning with leg pain, along with mild flu-like symptoms and irritability.
Anywho, the point is that I've been tapering my dose each day in hopes of being done drinking this stuff so routinely. When I recognized that I was a mild/moderate addict I was drinking tea of about 8g of powder a day. I cut that down to 4.5g the next day, and 3g the day after that, and really wasn't feeling a lot of discomfort. I've been sitting at 2.5 now for a couple days straight. I still get a pretty solid 2 hour buzz right after drinking it, but about 22 hours after consuming I can really start to tell that I'm missing something, but if I go back up to 3.5 then everything feels fine.
Can anyone explain the chemistry of this? Why does the body react more to cutting out 1 gram than it does to cutting out 3.5? I thought maybe its the portion of your total dose that your removing, but 3.5 to 2.5 is a smaller fractional decrease than 8 to 4.5, and I'm feeling the strain of 3.5 to 2.5 more after several days of acclimation than I did the 8 to 4.5 in an overnight change.
I've heard this is how it works before from someone who gets methadone pink drink from a clinic, and it seemed very odd to me then, and it still seems odd to me now.
Any vets care to comment?
-Jon
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