I took 10mg methadone at 8:30 pm, it is now 10:40 pm. I'm not really where I want to be as far as the high is concerned, is it safe to redose or should i give it another hour or two?

give it another hour or two

Methadone will sneak up on you my freind

With a little bit of opiate tolerance, 20mg should be just fine.

If you can handle 20mg of oxy you can handle 20 of mdone. Check your pupils in the mirror. Are they pin point? when you turn the light on and off do they:
A) rapidly dilate and contract(close to normal function)
B) stay pinned
C) slowly dilate and contract

If A you are safe to dose like four hours after.
If C you may want to only dose 5mgs or give it some mor etime to be safe.
If B you may have taken too much.


tolerance is important with methadone becaue it has a more powerful sedative effect than other opiates. Resipitory depression can also be stronger.

You must be catious with iniatial acute dosing(espeacially when non tolerant) and chronic dosing because of the build up of methadone over time when daily dosing.