Well... considering that their are approximately <50 uncontacted tribes left in the world, I'd say that all naturally occurring compounds have been discovered. Indigenous tribes/peoples usually have their ethnobotany on lock. I'm guessing the remaining uncontacted peoples aren't tripping on anything new.

As for synthetics.. who knows...probably still shit to be synthed.

Take salvia for example.

Salvinorin A was not even seriously considered, because it was not even an alkaloid.

I mean will there ever be new un-synthesized drugs out there that are undiscovered or something.

Several.

In fact, most suggestions indicate that the series of undiscovered drugs is literally infinite.

Or are there chemists out there that are working on a new drugs or something?

Yes. It's called lab tips.

Or are all the drugs known and already have their uses?

1. There are an infinite number of possible molecules.

2. There are a finite number of known molecules.

Therefore... ;)

Not that I've tried anything other than weed I'm just interested.

To the best of my knowledge, n-methyl(n,4-cyclopropyl)tryptamine remains unexplored.

Maybe you should synth it and risk your life to try it. Or, if you're not feeling that creative... both TIHKAL and PhIHKAL consist of more "it would be really nice if this were explored, but" than they do actual psychoactives...

While you are here, please tell me your assumption on:
What would happen if i were to decarboxylate D-Phen.

http://img237.imageshack.us/img237/8233/228pxdphenylalaninesvgkw7.png

I had a dream a few nights ago about a really cool plant that you could smoke just like weed except it was blue and you had to break open the thick stems of the plant to get to the fluffy inner part which I rolled a blunt of.

Come to think of it, they do make blue weed, and it is really cool. My dream plant was awesome too, I hope someone invents that.

Who is they?

Smurfs?

While you are here, please tell me your assumption on:
What would happen if i were to decarboxylate D-Phen.

Phenethylamine base. Same as l-phen.

Form the acyl halide, perform a friedel-crafts itnramolecular cyclatization, and reduce the ketone, 'n you'd have the stimulant 2-aminoindane. Perform the intramolecular halogenation of the 2-position and use this to cyclatize on the amine, however, and one would have dihydroindole-2-methanoic acid. No one knows what the fuck that shit does.

Reduce that, and you might have 2-methyldihydroindole... which is probably a stimulant as well, but no one knows really what the hell that shit does, either.

And then there's the a-methyl-aziridine. Everyone knows what the b-carbon aziridine does, and it kinda sucks... but there's reason to believe that the gamma-aziridine would be potentially more interesting.

'n I'm probably spelling aziridine wrong. Oh, the amide remains untested, as does the 2,3-diamine of amphetamine, all of which could be made from phenylalanine.

Don't make diphenylalanine anhydride or its derivatives, though, without further reduction, as it should be carcinogenic as fuck, possibly with other problems.

according to the theory of evolution there will be new unsynthesised substances in the future

Who is they?

They are.

They are.

You mean they is?

When you look at the sheer number of chemical possibilities, you would have to also consiter what the brain can handel. There are many realms of the mind that have yet to be tampered with. Ex Salvinorin A and other salvia-like compunds. Chemically sure the possibilities are endless but your brain eventuallly has its limits.


Or maybe I could be totally wrong and new drugs could create new receptors in the brain. Highly unlikely though, maybe in the future?

When I'm high as shit I like to think of all the drugs that may or not be in space.

I know some crazy ass planet out there has some potent hallucinogens. That would be awesome.

You mean they is?

Yeah, sorry.

I wouldn't say theres too many undiscovered psychoactive plants (theres most likely some out there though) but God only knows how many compounds are just waiting to be discovered. LSD was discovered by shear coincidence. If Hoffman didn't accidentally ingest it he woulda never discovered its psychedelic properties.

I don't think I could handle SUPER meth. Meth is super enough.

Omg I was seriously about to post "Dude think about the alien drugs we could make" except you made it more elaborate

I bet there is shit out there that could have you in a salvia state forever, until you DIE!


Stupid noob: nooo-oooo-oooo

someone man up and try L2D

Send me some. I would totally try it if I could find it.

I've always wondered about what kind of weird plants/chemicals may be lurking deep in the oceans, and as someone above me said... outer space.

Anything is possible, who knows what the future will bring...

I can't wait till someone invents Substance D

i would say deep in the rain forests, and the depths of see probably hold undiscovered natural chemicals.