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| Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference. |
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#1
 2008-08-04, 00:51
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serotonin-dopamine reuptake inhibitor
..........
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#2
 2008-08-04, 01:29
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spl1ff 
Regular
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Re: serotonin-dopamine reuptake inhibitor
correct me if i'm wrong, but isn't meth an sdri?
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#3
 2008-08-04, 01:39
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Re: serotonin-dopamine reuptake inhibitor
Dextro-methamphetamine hydrochloride is a potent central nervous system stimulant that reverses the direction of flow in the norepinephrine, dopamine and serotonin transporters, sending these neurotransmitters from the vesicle into the synapse instead of storing them in the vesicle for future use. The compound also inhibits the reuptake of the transmitters into the pre-synaptic (sending) neuron, causing them to remain in the synaptic cleft longer. The resulting increased levels of dopamine and norepinephrine in these synapses affect neurochemical mechanisms responsible for regulating heart rate, body temperature, blood pressure, appetite, attention, mood and responses associated with alertness or alarm conditions.
^^from wiki
i think that means its an sndri, like tesofensine and bresofensine. there are sndris, snris, ndris, ssris, dris, nris, yet no sdris.
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#4
 2008-08-04, 03:29
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Aerogone 
Regular
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Re: serotonin-dopamine reuptake inhibitor
Sure, dopamine re uptake inhibition is done by: Coke & Ritalin
Meth on the other hand reverses the re uptake of dopamine, making it that much more addictive.... the amount of dopamine that you pump back out is INSANE....
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#5
 2008-08-04, 03:38
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Aerogone 
Regular
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Re: serotonin-dopamine reuptake inhibitor
And as for stopping the breakdown of dopamine... WTF do you think MAOI's do... Hu?
Interestingly I have recently recommended, and shipped my mother a few sets of an MAO-B inhibitor. Works wonders for the aging/empty-nest/menopausal depression.
aerogone check yo email
Will do!
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