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Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference.

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 #1 
Old 2008-07-23, 02:14
Aerogone Aerogone is offline
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Default How many of you actually know about marijuana from its pharmacological stand-point.

When the member ThetaReactor, made a mistake, and surely no-one actually knew, i understood that probobly no-one gave a crap....

Honestly, how many of you know that THC is not an alkaloid?

Or perhaps that, dear opiate-philes, that your arch enemy APAP works with none other but "canabinoid" circuit.

go to the thread and have a look


THC
http://upload.wikimedia.org/wikipedia/en/thumb/4/4c/Tetrahydrocannabinol.svg/242px-Tetrahydrocannabinol.svg.png
Show me... nitrogen:)

We all "expert tokers" included know diddly squat, about the pharmacological actions of marijuana, even when we think we do.

Any monkey can understand: "THC GET ME HIGH" mentality.

But dam there is sooo much more to this category of plants then you think possible. From actual alkaloid differences in plant make up, to extensive canabinoid circuit exploration, by modern science.
 #2 
Old 2008-07-23, 02:18
Konnfee Konnfee is offline
Regular
 
Default Re: How many of you actually know about marijuana from its pharmacological stand-point.

Gratz?
I just smoke the shit.
 #3 
Old 2008-07-23, 02:20
36fuckin5 36fuckin5 is offline
Regular
 
Default Re: How many of you actually know about marijuana from its pharmacological stand-point.

Honestly, how many of you know that THC is not an alkaloid?


It's an essential oil. A lot of us know this, but we got these discussions out of the way a long time ago. The effects, pharmacological and subjective, of psychedelics are much more fascinating.
 #4 
Old 2008-07-23, 02:32
MongolianThroatCancer MongolianThroatCancer is offline
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Default Re: How many of you actually know about marijuana from its pharmacological stand-point.

http://www.ccrmg.org/journal.html

this has some good info IMO
 #5 
Old 2008-07-23, 02:32
Moderator
 
Connecticut
Default Re: How many of you actually know about marijuana from its pharmacological stand-point.

heres food for thought. the act of getting high off THC is THC saturation of your blood stream...


which explains the theory of why first time smokers may not get high even with proper technique, they'd have to smoke more than regulars, which also explains the theory of reverse tolerance, see all us potheads have fat cells stored with THC, so we saturate quickly...
 #6 
Old 2008-07-23, 02:40
Regular
 
Default Re: How many of you actually know about marijuana from its pharmacological stand-point.

cool... tell me how to get higher?


which explains the theory of why first time smokers may not get high even with proper technique, they'd have to smoke more than regulars, which also explains the theory of reverse tolerance, see all us potheads have fat cells stored with THC, so we saturate quickly...
Ya i read that with GHB some people have to take it 4 or 5 times before they feel effects becuz there body doesnt digest it right or something. But some ppl it works 1st time
 #7 
Old 2008-07-23, 03:54
spl1ff spl1ff is offline
Regular
 
Default Re: How many of you actually know about marijuana from its pharmacological stand-point.

When the member ThetaReactor, made a mistake, and surely no-one actually knew, i understood that probobly no-one gave a crap....

Honestly, how many of you know that THC is not an alkaloid?



of course, why else wouldn't it come out from an acid/base extraction?



Or perhaps that, dear opiate-philes, that your arch enemy APAP works with none other but "canabinoid" circuit.




now THAT is interesting.

even the existence of cannabinoid receptors is mind blowing.

and the correct term is "opiophile"
 #8 
Old 2008-07-23, 03:58
laundrysoap laundrysoap is offline
Regular
 
Default Re: How many of you actually know about marijuana from its pharmacological stand-point.

Hey dipshit, the fact that THC isn't an alkaloid has nothing to do with its pharmacology. Therefore, your title is fucking retarded.
 #9 
Old 2008-07-23, 15:01
Moderator
 
mah compound
Default Re: How many of you actually know about marijuana from its pharmacological stand-point.

LOL What forum is this?


Oh, and also, you should know as well as anyone that the definition of an alkaloid is very broad, and though the STRICT definition is that it must be nitrogenous, it is not in fact a rule set in stone. Though it may be an error, or stretch of terminology, it is not entirely wrong to call THC an alkaloid.
 #10 
Old 2008-07-23, 17:10
Regular
 
Australia
Default Re: How many of you actually know about marijuana from its pharmacological stand-point.

When the member ThetaReactor, made a mistake, and surely no-one actually knew, i understood that probobly no-one gave a crap....

Honestly, how many of you know that THC is not an alkaloid?

Or perhaps that, dear opiate-philes, that your arch enemy APAP works with none other but "canabinoid" circuit.




THC
http://upload.wikimedia.org/wikipedia/en/thumb/4/4c/Tetrahydrocannabinol.svg/242px-Tetrahydrocannabinol.svg.png
Show me... nitrogen:)

We all "expert tokers" included know diddly squat, about the pharmacological actions of marijuana, even when we think we do.

Any monkey can understand: "THC GET ME HIGH" mentality.

But dam there is sooo much more to this category of plants then you think possible. From actual alkaloid differences in plant make up, to extensive canabinoid circuit exploration, by modern science.

lab tips is thatta way --->
 #11 
Old 2008-07-23, 22:07
Pooter Pooter is offline
Regular
 
Default Re: How many of you actually know about marijuana from its pharmacological stand-point.

But there are analogs that act on the cannabinoid receptors that DO contain Nitrogen, for example, WIN 55,212-2. WIN 55,212-2 is very active as a full agonist too. These are compositional differences don't affect the pharmacology of the substance in the way that you think it does.
 #12 
Old 2008-07-24, 05:45
laundrysoap laundrysoap is offline
Regular
 
Default Re: How many of you actually know about marijuana from its pharmacological stand-point.

Aerogone is such a fag.
 
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