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Laboratory Tips Safety proceedures, test reagents, drilling rubber stoppers, bending glass tubes, etc. Contributed to by chemists.

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 #1 
Old 2008-07-06, 13:47
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Default Demethylation of codeine

Is there any alternative to pyridine HCl in the conversion of codeine to morphine? Pyridines highly impracticle since its so toxic and its definitely not OTC. Anyone here heard of any alternatives?
 #2 
Old 2008-07-06, 15:34
Von Bass Von Bass is offline
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Default Re: Demethylation of codeine

Boron Tribromide. That's also toxic and not OTC, so methinks its not what you're after.

http://psychedelichosting.info/Ionium/Rhodium/chemistry/codeine2morphine.html

I'm not the one to say, but you should search the forums and the rhodium archive before asking questions like this, the conversion of codeine to morphine has been discussed multiple times over.
 #3 
Old 2008-07-07, 19:33
FullMetalJacket FullMetalJacket is offline
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Default Re: Demethylation of codeine

Quote:
Originally Posted by MrSparkle
Is there any alternative to pyridine HCl in the conversion of codeine to morphine? Pyridines highly impracticle since its so toxic and its definitely not OTC. Anyone here heard of any alternatives?


O RLY?

google a little, read a little more, and go decarboxylate a few kilos of niacin.
 
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