I've noticed an increase in the frequency of pharmaceutical commercials advertising a treatment for this "restless leg syndrome". Seriously, restless legs? "Yeah Doc, my legs seem to be a little active, can you give me something?"I did a little research on RLS prescriptions and the active ingredient is a dopamine D2 and D3 receptor antagonist, meaning it induces the brain to produce dopamine. It was originally used for parkinson's disease patients. I tried to find out exactly which receptors THC acts on but with no luck.

So totse, does anyone know what specific domamine receptors THC binds to and have I found a Marinol substitute?

Requip for the lose.

I thought THC binds to the cannabinoid receptor CB1 in the central nervous system, not dopamine receptors, at all.



http://www.chemistrydaily.com/chemistry/THC

this...he beat me to it

epic fail.

A good amount of docs script Klonopin for RLS if Requip is ineffective.

I think I have RLS... it keeps me awake at night sometimes because I gotta keep moving, its mostly like my legs start to hurt if i don't move them a little bit all the time.

I'm constantly pumping my foot up and down too, like a nervous twitch. I can't stop it sometimes, like I'll have to physically hold my leg down to get it to stop thumping.

Weed seems to ease it, but doesn't totally cure it. All in all though, it isn't so bad. I never even thought about getting treated for it until I saw the commercials.

I have a doc appointment sometime soon, I'll ask what they can do about it then.

Some people are easily influenced by commercials. Keep feeding the corporate train yuppie.

One of the potential side effects for that RLS drug is increased risk of gambling.

I'm srs.

yes, because they act on dopamine. excessive gambling is a symptom of mania, along with hypersexuality and excessive spending. antipsychotic drugs that treat these symptoms suppress dopamine, doing pretty much the opposite of the RLS drug.

yes, because they act on dopamine. excessive gambling is a symptom of mania, along with hypersexuality and excessive spending. antipsychotic drugs that treat these symptoms suppress dopamine, doing pretty much the opposite of the RLS drug.

I know that, but it's funnier when you don't explain it.

I get that, but only if i haven't done any exercise that day. Jog or take up a sport or something.

I always viewed RLS as an excuse or reason for them to manufacture and sell more pharmaceuticals.

I know that, but it's funnier when you don't explain it.

Indeed, Darkus. Because then they will be like "Oh yea dude, I gamble all the time. I'm so RLS."

I always viewed RLS as an excuse or reason for them to manufacture and sell more pharmaceuticals.

Some people are easily influenced by commercials. Keep feeding the corporate train yuppie.

Some people are easily influenced by commercials. Keep feeding the corporate train yuppie.

Heh... you aren't very smart are you?





I think mine might be caused by a huge influx of caffeine everyday. Stimulants make you move. Like crack addicts can't sit still for too long without twitching or some shit.

I think mine might be caused by a huge influx of caffeine everyday. Stimulants make you move. Like crack addicts can't sit still for too long without twitching or some shit.

And you are such an all knowing drug wizard. Give me a fucking break. Maybe you should stop taking such a "huge" amount of caffeine instead of wasting money on needless prescriptions? Your theory on RLS is hilarious.

Some people are easily influenced by commercials. Keep feeding the corporate train yuppie.


Mhmm. I guarantee you that as soon as those commercials aired, a couple hundred thousand shit-heads said to themselves "Wait a minute...MY LEG GETS TINGLY SOMETIMES!!1!!1!11!"

ok


how many people in here have leg twitches or find it satisfying to move their legs for no reason?

i know i do








all the people who laugh, simply dont have it.

i blame it more to be a jittery mother fucker, rather than any old disease...


however its painful when sleeping and not moving in your sleep drunk..

however its painful when sleeping and not moving in your sleep drunk..

Amen.

About to experience that in like 3 minutes actually. :(

So, can these RLS drugs be abused?

Try exercise. Seriously, i never get it if i've been playing football that day.