I was just thinking about Joepedo's old theory; on how we could make as much dopamine as we wanted in our brains, and all we'd have was "pump" ourselves full of massive doses of amino acids along with copious varieties of vitamins and fun foodstuffs.
Anyone rember the green potato?

-More importantly-
Did anyone eat the green potato?

And if you didn't have the means of getting hold of/growing one, we could always eat the vines of a tomato for our wonderful solanine/tomatine fix.

Anyway: my point is,
If you want to get a high by producing excessive levels of dopamine in the brain, stick to the Real Fucking recreational drugs.
Y'know, the ones that are effective dopamine reuptake inhibitors?
Not a vegetable OD?..

You get my point.
But JP bear in mind if you make a cocktail that actually works im soz fur dowting u i luv u joe. Etc.

i just drank like a gallon of ketchup, im so throwed.

I got L-Phen and L-Huperzine (in place of a moldy potato) and took the entire stack that was recommended in that thread... didn't do anything noticeable. If you want to feel good, stick to the tried and true drugs.

True dat

Keep on doing what you KNOW works...

lol you guys got trolled by JP.

did he suggest bananadine as well?

LAWL!

OP, what the fuck are you going on about?

You misused that semicolon.

hey email me at pyroskater77@hotmail.com

i wanted to ask you some questions about the houston scene

I never bought it, especially after reading one of the chemicals was a poison, forgot which one it was though.

Probably solanine, eh? Yeah it's a poison but so are most things.

I tried it, with extracted and purified solanine form green potatoes grown under blacklight for two weeks until totally green.

it could easily have been a placebo, and I'm yet to institute a double-blind test by recompounding all the components into one or more pills, but I certainly noticed a subtle change in the effects of a number of drugs as well as a general feeling of well-being and smoother recovery times from a number of binges. Hell, even if it doesn't do shit, i'm getting some extra vitamins so who am I to complain, really?

BUMP from teh OhPee.

JP- please may you give some kind of contribution to the thread?
Eg-
"Sorry guys, i guess i messed up on the whole l-phen thing"
or even
"Haha, i pwned you all, kidiots.."
Or, the ever-optimistic (..This one preeze.)
"I've figured out how i originally messed up the theory! i've reworked it and now it is comparable to high dose OC!"

After all- it is aimed in your general direction.. :)

Aye, I wanna know what's up too... he seemed so positive that it would be an amazing experience, and like 5+ people said it works... but none of them seemed blown away. So I tried it myself, and there were zero noticeable effects. People were having a placebo, if anything.

You all miss the point of the combo, its not meant to fuck you up....

If I remember correctly, the OP of that thread asked if dl-phenylalanine had recreation potential - to which JP replied, hell yes.

I think phenylalanine has some potential for use that is being overlooked. It's not some obscure nutritional supplement. It's a powerful amino acid which is proven to be linked with dopamine. JP's cocktail thread wasn't the first time I'd ever heard phenylalanine mentioned and I hope it's not the last.

If I remember correctly, the OP of that thread asked if dl-phenylalanine had recreation potential - to which JP replied, hell yes.

I think phenylalanine has some potential for use that is being overlooked. It's not some obscure nutritional supplement. It's a powerful amino acid which is proven to be linked with dopamine. JP's cocktail thread wasn't the first time I'd ever heard phenylalanine mentioned and I hope it's not the last.

haha, yeah, when I had easy access to free amps all the time I'd be all sucking on mints containing pheylalanine hoping for a better dopamine rush

and plus you have to have something to suck on/chew on that's not yr tongue/cheeks

If JP was trolling, I'll be really pissed. I've been saving that recipe in a Word Document for almost year now.

Someone get his attention in LT or some other forum FFS.

lolol

BUMP from teh OhPee.

JP- please may you give some kind of contribution to the thread?
Eg-

A'aight.

'course, you'll probably be somewhat disappointed that my contribution is going to be "actually, I'm still secure and confident." I'm getting the feeling that this is not the response you were hoping for, but... hey. The majority response was actually positive; I think ferret took over the data compilation after I started slacking in harvesting the numbers 'n procedure....

There are two uncontrolled variables in the matter, 'n those are diet 'n the state of one's body's biofeedback mechanisms. Most of the actual fun of dopamine (as opposed to 'the excessive masturbation of dopamine,' which is pretty hedonically neutral and vacant) is dependent on one's serotonin levels at the time...

...but if you really want an answer to "can my body even do anything with this" - pop it during a meth crash. You'll get an answer, for your body, rather quickly.

Regarding your last suggested response, though... there has been one minor breakthrough... the threshold for tyrosine increase (http://www.totse.com/community/showpost.php?p=10158420&postcount=5) was dug up (10mg/kg total pa intake, which means for a 70kg person, a minimum of 700mg needs to already be in one's diet for there to be an increase), and it led to people discussing it in terms of mg intake per mg/kg increase, which is a pretty good way to look at it...

...but no, sorry to disappoint, but no retraction, no apologies. Drop a gram 'n wash down the supplement stack with a pot of strong coffee in the throes of a hard meth comedown if you want to see if your body can process amino acids properly. Closest there is, though, is an enormous increase in suggested dosage in cases of dietary deficiency in light of Zello, Pencharz, 'n Ball's 1990 work - as prior noted, you've got to have 700mg in your blood minimum from your diet before it'll change a thing, for a 70kg person.

According to the data from the first thread, the majority of people are within less than their dose of the dietary minimum.

But, no... I'm happy with it, 'n I don't intend to recant while I'm still a puddle of smiling calm bliss. When I run one system into the ground, I just work on what I've neglected 'n come back to it later... 'n I'm more than happy chatting with those who enjoy it. It's worth tinkering with 'till you get your body to work.

Run the hardware on manual, then drop the drugs in.
- jp

hey joepedo, if someone was on prozac, (sertraline) would that intensify the effects of the cocktail, ya know, with the increased seratonin levels

What's the point of taking the L-phen. combo, if L-dopa is available?

Hey JP, few questions for you if you don't mind.

I just got finished with about three months of 1500mg tyrosine + the other stuff daily and now I'm switching to DLPA. I only found one response to someones question of "Is DLPA at high doses (1000mg) harmful if taken all at once," I'm pretty sure you responded that it's best to space it out, I'm just wondering dosage wise what should one space it out into and it it should be taken with more caffeine in all the bumps. I originally was using the DLPA but I had total dysphoria, that kind of scared me off, I'm guessing I forgot the magnesium on that day but kind of curious what that was. One more, lol, since Prozac takes like five weeks to really start working on behavior is there something similar with this combo (sunflower oil included, about 3tsp/day for me)

Oh, and, I also wish to learn how to run my mind and body manually. :) (or at least be pointed in the right direction)

(sry for hassling u so much, still reading about game theory)

Possibly, though it would depend somewhat on *why* they were put on prozac in the first place...

...now, a non-depressed person with a healthy diet eating ecitalopram... hmm... ;)

What's the point of taking the L-phen. combo, if L-dopa is available?

Almost nothing. ;) The finished product skips a lot of hassle, in fact, unless one wants a smidge of phenethylamine to go with it.

I only found one response to someones question of "Is DLPA at high doses (1000mg) harmful if taken all at once," I'm pretty sure you responded that it's best to space it out, I'm just wondering dosage wise what should one space it out into...

"enough so that one doesn't get painful watery diahrrhea from single-dose excessive point metabolism," basically. It's different than all the other increases in intestinal motility that can come of having adequate dopamine/noradrenaline/serotonin/melatonin. You'll know if it happens, trust me. Gut ache + squirting clear liquid.

I originally was using the DLPA but I had total dysphoria, that kind of scared me off, I'm guessing I forgot the magnesium on that day but kind of curious what that was.

Possibly immediate decarboxylation to phenethylamine leading to a depressive amphetamine crash which your body could not manufacture enough dopamine to compensate for. Incidentally, with the racemate, this is the *only* metabolic option for the dextro isomer.

One more, lol, since Prozac takes like five weeks to really start working on behavior is there something similar with this combo (sunflower oil included, about 3tsp/day for me)

Sunflower seed. Eat fuckloads of it. Take stimulants (coffee, ascorbate, amphetamine, w/e) if this produces fatigue.

Oh, and, I also wish to learn how to run my mind and body manually. (or at least be pointed in the right direction)

PubMed FTW. Find out how the molecule is made, what its secondary messengers are, what alters receptor sensitization, what inhibits/induces any part of the p450 spectrum involved, what inhibits/induces any enzymatic transcription, etc, etc, etc, etc!

:)

Out of the ten times I tried it, getting every ingredient and dosage right, it worked wonderfully for me twice, 4 times it made me feel like absolute shit, and the rest of the time it didn't do anything.

I believe in the theory. I think it's entirely possible to get good results, the problem is there are so many variables that it's too inconsistent to be worth the money and energy.

This combo does work. I've done it lots of time myself with the majority of the results being good. However everyone is different. Differences in brain chemistry or a diet that is too rich or too poor in certain nutrients can change the effects or completely negate them.

That being said these things seem to help me feel the effects:

*Drinking green tea (a COMT inhibitor) is supposed to increase the amount of dopamine that actually gets to your brain. just be careful to drink it a while after you pop the iron b/c it can affect absorption of iron. Other COMT inhibitors should help with this as well. i remember JP mentioning some common OTC COMT inhibitors but i don't remember what the were.

*Vitamin C- not too sure on the science about this one but it seems to help.

*Taking more caffeine- a lot of people have a significant tolerance to caffiene. If you are one of these people then you need to take more.

*St. John's Wort- This was in his original cocktail but JP said its mostly just for if you feel overstimulated. I feel that it really adds something to the combo no matter what especially when you start dosing with Vit C as well.

*and finally instead of taking Huperazine A take some fucking green potato. Its much easier to titrate your dose this way. And its easier to take a few more bites of potato to re dose your Acetylcholinesterase inhibitor than to pop another pill. Also since huperazine A is an extract from a plant its potency is questionable.

Oh yeah JP do you know of any Dopa-decarboxylase inhibitors that you don't have to have parkinsons to have access to?

so after reading mari juana say whats the point of if L-dopa is available, and you saying nothing really, then this dude saying 4 out of 10. can you go more into detail about L-dopa JP. i did do my research a good bit, but i understand shit more coming from your keyboard. maybe L-dopa should be looked into more? its side effects scare me though.

edit: i mainly quoted this guy because he spoke of the variables part. maybe L-dopa will help with the variables.

Lol, you should all have known he was trolling.

JP, trolling? do you know who he is on here?

Sorry for resurrecting this JP- but it really, really has caught my interest again.

I've been thinking the same thing for a while now, as to why the L-Phen combo never took off.
Thing is, your theory is how you can PRODUCE dopamine within the brain but not RELEASE it- the drug itself is just a different means of dopamine production available to those who can not produce it naturally- it doesn't get you high, just creates more dopamine within the brain- such as needed those with Parkinson's, as they can't produce it naturally. I believe this is why L-Dopa itself has never been used recreationally.
The higher levels of dopamine are there- your brain is not using them, though...

I possibly am completely wrong. Then again, this is just a thought from someone who never experienced anything positive from L-Phen surprise.
Help?