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Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference.

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 #1 
Old 2008-06-18, 01:09
DoctorMayhem DoctorMayhem is offline
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Default trazodone interactions with psychedelics

Does anyone have any experience with this?
I know that SSRI's can greatly diminish the effects of psychedelics (although I have a friend on wellbutrin who still trips just as hard as anyone else), and I experienced this when I smoked DMT while on Lexapro and had very minor effects.
Seems like trazodone is a 5HT2A antagonist, so this makes me wonder if it could diminish the effects of psychedelics; LSD, psilocin, etc being agonists of said receptor.
I'd also like to know about it affecting MDMA, which I really dont think it will it working on 5HT1A from what I can tell.
But, I dont know shit about all this and havent really read anything about receptors and all that until about half an hour ago so any input would be nice.
:)
 #2 
Old 2008-06-19, 07:34
DoctorMayhem DoctorMayhem is offline
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Default Re: trazodone interactions with psychedelics

by the power vested in my by the website of totse, i bump this thread.
 
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