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Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference.

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 #1 
Old 2008-05-24, 00:00
Methface Methface is offline
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Default oxycontin time release removal

Im sure this gets asked all the time, but I need the best way to remove the time release on an O.C 80 tab (the green one) without turning it into gooey paste, or mixing the SR with the powder. I can snort, or parachute the powder. Not injecting. This will be split up between three people, two first timers. I've done it before.

Hit me with some precautions, although im well aware of the dangerous ones.

P.S, we were thinking about taking some benadryl before hand, although I know this increases the chance of respiratory depression, but has anyone tried this and had bad effects, please note dose.
 #2 
Old 2008-05-24, 00:08
Zapphle Zapphle is offline
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Default Re: oxycontin time release removal

Suck on it and rub the outer coating off.

Take low doses of benadryl to help with the itching, and low doses of DXM if you want to help from building tolerance.
 #3 
Old 2008-05-24, 00:16
Obscura Obscura is offline
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Default Re: oxycontin time release removal

Suck on it and rub the outer coating off.Is the outer coating actually responsible for the time release properties of the pill? Something tells me no.
 #4 
Old 2008-05-24, 00:17
Methface Methface is offline
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Default Re: oxycontin time release removal

Are you sure it's just the coating? The last time I had an oxy 80 was a few years ago, it looked different I think, more spherial, but maybe not. The guys I did it with heated it up, mentioning somthing about melting the binders, then rubbed it in some water then rubbed the coating off.

But from what I've read so far, sucking the coating off until it's white and then crushing it is good enough.

Doesn't it seem stupid though, for an-anti abuse mechanism to be so easy thrwarted.
 #5 
Old 2008-05-24, 00:33
robinhoody robinhoody is offline
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Default Re: oxycontin time release removal

The coating is not the time release.

If it's Purdue or Watson, you can seriously just crush it up and you'll be set.
 #6 
Old 2008-05-24, 01:59
Envision Envision is offline
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Default Re: oxycontin time release removal

Like RobinHoody said it's not the coating that makes it time release but other crap mixed in with the pill. Most Oxy's you can just crush up and do as you please but if you get those damn Tevas they gel the fuck up and are a bitch to do anything with. Benadryl taken 30 to 45 minutes before your dose of Oxy will potentiate it but I prefer Tagament. Also if you take Benadryl after you've popped your Oxy it will help you nod out.
 #7 
Old 2008-05-24, 04:49
Shans283 Shans283 is offline
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Default Re: oxycontin time release removal

I scrape the outer casing off with a knife...make sure you don't scrape any powder off though..
 #8 
Old 2008-05-24, 18:23
Methface Methface is offline
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Default Re: oxycontin time release removal

I have a CDN 80 (small round grey-green tablet, white underneath when scraped). i live in nova scotia. Im sure it's oxycontin 80mg, but the it might not be the ones you can snort. I've seen other ones from the same brand crushed and it WAS slightly gummy, like a skittle.
Is there anything I can do to stop that? Someone must know
 #9 
Old 2008-05-24, 19:00
Envision Envision is offline
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Default Re: oxycontin time release removal

Quote:
Originally Posted by Methface
I have a CDN 80 (small round grey-green tablet, white underneath when scraped). i live in nova scotia. Im sure it's oxycontin 80mg, but the it might not be the ones you can snort. I've seen other ones from the same brand crushed and it WAS slightly gummy, like a skittle.
Is there anything I can do to stop that? Someone must know


If it's a OC that gels look up Ike's "Blue Oxy" post on opiophile
 #10 
Old 2008-05-24, 19:47
ilovechronic ilovechronic is offline
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Default Re: oxycontin time release removal

Quote:
Originally Posted by robinhoody
The coating is not the time release.

If it's Purdue or Watson, you can seriously just crush it up and you'll be set.


Yep, the WHOLE pill is a time release system. Even crushed it still would NOT hit or absorb as fast as ooxy instant release. I believe they call it a wax matrix. It is the same with ms contin. Each molecule of the drug is incased in a wax matrix.
 #11 
Old 2008-05-24, 21:00
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East Bay, CA (Bay Area)
Default Re: oxycontin time release removal

It's a Purdue. Just crush it up and use the potentiation formula and your set.

That said, to get the ABSOLUTE MOST out of your opiate, try N0 W4RN1NG's patented opioid potentiation formula:
T-45) 600mg Tagamet HB(Cimetidine HCl), a large glass of tonic water (or another source of quinine), and a large glass of (white) Grapefruit juice, preferably from concentrate.
T-35) 30mg DXM HBr, 4mg CPM, 25mg Benadryl(Diphenhydramine HCl), 330mg Naproxen(Aleve).
T-20) 2 Tums OR 1.5 Tbsp. of Baking SODA. (Obviously this step only applies if you are eating your opes)
T-0) Parachute\chew\rail\bang your opiate\opioid.
T+10) Smoke a bowl or two. Not more, you don't want to over power it.
 #12 
Old 2008-05-25, 00:47
ilovechronic ilovechronic is offline
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Default Re: oxycontin time release removal

Quote:
Originally Posted by Thought Riot
It's a Purdue. Just crush it up and use the potentiation formula and your set.

That said, to get the ABSOLUTE MOST out of your opiate, try N0 W4RN1NG's patented opioid potentiation formula:
T-45) 600mg Tagamet HB(Cimetidine HCl), a large glass of tonic water (or another source of quinine), and a large glass of (white) Grapefruit juice, preferably from concentrate.
T-35) 30mg DXM HBr, 4mg CPM, 25mg Benadryl(Diphenhydramine HCl), 330mg Naproxen(Aleve).
T-20) 2 Tums OR 1.5 Tbsp. of Baking SODA. (Obviously this step only applies if you are eating your opes)
T-0) Parachute\chew\rail\bang your opiate\opioid.
T+10) Smoke a bowl or two. Not more, you don't want to over power it.


seriously you do not need tums/baking soda and tagemet. the tagemet is an acid reducer and you alread have a double dose liste so why would you even need both? Thats like making your stomach completely basic. Weed cannot over power opiates it can only complement them.

Naproxen or anyother nsaid would only be necessary to pontentiate analgesia but it will NOT get you higher. It will only help a little with pain.
 #13 
Old 2008-05-25, 10:33
Dies Irae Dies Irae is offline
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Default Re: oxycontin time release removal

The tagamet potentiates it aside from being an antacid. Slows down how fast its metabolized, making it last longer. This is the main reason you take it

The tums is more for the antacid effect.

Still seems unneccesary to take the tums.
 #14 
Old 2008-05-25, 19:44
ilovechronic ilovechronic is offline
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Default Re: oxycontin time release removal

Quote:
Originally Posted by Dies Irae
The tagamet potentiates it aside from being an antacid. Slows down how fast its metabolized, making it last longer. This is the main reason you take it

The tums is more for the antacid effect.

Still seems unneccesary to take the tums.


I promise you if you take a double dose of tagmet 45 minutes befor you take the opiates/oids you will not need to take tums or baking soda also. A double dose is plenty enough to reduce acid.
 #15 
Old 2008-05-25, 19:56
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East Bay, CA (Bay Area)
Default Re: oxycontin time release removal

Fuck it, here's the rest of NO WARNING's orginal post:

That said, to get the ABSOLUTE MOST out of your opiate, try N0 W4RN1NG's patented opioid potentiation formula:
T-45) 600mg Tagamet HB(Cimetidine HCl), a large glass of tonic water (or another source of quinine), and a large glass of (white) Grapefruit juice, preferably from concentrate.
T-35) 30mg DXM HBr, 4mg CPM, 25mg Benadryl(Diphenhydramine HCl), 330mg Naproxen(Aleve).
T-20) 2 Tums OR 1.5 Tbsp. of Baking SODA. (Obviously this step only applies if you are eating your opes)
T-0) Parachute\chew\rail\bang your opiate\opioid.
T+10) Smoke a bowl or two. Not more, you don't want to over power it.
In depth explanation:

The Tagamet HB (Cimetidine) is a broad CYP450 inhibitor. This basically means it 'clogs' the enzymes that metabolize opiates\opioids and clear 'em out of the body. Tagamet HB tablets are 200mg each, so the recommended 600mg is 3 tabs. They're OTC, and you can get a box of 50 generic 200mg cimetidine tabs at CVS for like $5.49.

Quinine is an ingredient in tonic water, and functions the same way as Tagamet. It inhibits the CYP450 set, more specifically, CYP2D6. It doesn't 'clog' as many enzymes as Tagamet does, but it STRONGLY 'clogs' CYP2D6, which is the MAIN enzyme for opiates like oxycodone, heroin, hydromorphone, etc. A large glass of straight tonic water is plenty. I prefer the "Vintage" brand. You can buy a liter of tonic water at any grocery for like $2.00.

White grapefruit juice contains three ingredients that clog the CYP450 set. However, it doesn't clog CYP2D6 too well, which is the main one for most opes. It does strongly 'clog' CYP3A4 nicely though, and although that's almost an 'auxillary' enzyme for alot of opiates, it definitely helps out. Again, it's cheap. Go to any grocery store and you should be able to get a nice big bottle of 100% whitre grapefruit juice from concentrate for like $2.50-$3.50.

An important thing to note for the grapefruit juice is the percentage of juice. A lot of companies make "White grapefruit juice" that is basically water, corn syrup, and like 10% juice. This is almost a waste of your money. You want it to say 100% juice, and also, you want to make sure it's 100% white grapefruit juice! A very common business practice for juice companies is to create 'juice cocktails'. These are beverages that are MAINLY cheap filler juices like apple and pear, with the advertised fruit only partially accounting for that '100% juice' the bottle sports so vividly. Look in the ingredients list, and make sure the only juice in there is white grapefruit, preferably from concentrate.

Nutritionally, juices from concentrate are usually not as good. However, for one reason or another, grapefruit juice from concentrate can contain 25%-40% MORE naringin, bergamottin and dihydroxybergamottin; the three enzyme inhibitors present in white grapefruit.

Now, some of you may be wondering WHY 'clogging' these enzymes is so beneficial. Basically, by slowing or even completely stopping the metabolization of opiates, they last MUCH longer. Also, blood plasma levels of opiates have been shown to vastly higher when the CYP450 set is strongly inhibited; meaning their is a higher peak, and it lasts longer.

It's a win-win situation, trust me. ^_^

On to the other shit. Benadryl(diphenhydramine HCl) and CPM(chlorpheniramine maleate) are both over-the-counter anti-histamines that increase the analgesic and euphoric properties of opiates to some extent. They also help cut down on the ope-itch. In addition, these guys also slightly inhibit subset CYP2D6.

Seeing a pattern here?

DXM (Dextromethorphan HBr, Robitussin, Zicam, etc.[not that it needed an intro on this board]) has a special effect in this formula. Although it doesn't inhibit the CYP450 set to any appreciable extent, it does contribute to analgesia and euphoria for all major opiates. Also, it has been shown to prevent the build up of tolerance! 30mg of DXM a good half hour or so before dosing will definitely slow any tolerance build up if you use this method every time. And with opiates, that's a VERY big deal.

The Naproxen(Aleve) adds to the analgesia and euphoria. Aleve comes in 220mg tabs, so by 330mg I mean one-and-a-half tabs.

The tums\baking soda is only necessary if you're eating the opiates in question. Basically, they lower the PH of the stomach\GI tract [well, technically it raises the PH, but ya know what I mean] which allows more of the opiate to be absorbed into the blood.

It's fine to smoke a little bud, but too much ruins the high IMO. And when I say a little, I mean like .2g, tops. If you have a moster tolerance, titrate accordingly, but if you smoke a few times a week .3 will be perfect.

To further breakdown all this pre-dose potentiation, I'll make it easy for you guys and just tell ya how many pills to take, and the exact way I consume them
T-45) 3 200mg Cimetidine pills, washed down with a HUGE tonic water\white grapefruit juice cocktail.
T-35) 1 Coriciden Cough & Cold Low Blood Pressure, 1 Benadryl, and one and a half Aleve.
T-20) 2 extra strength Tums if I'm popping the opes.
T-0) Rail\pop those shits.
T+10) *Smokes a bowl*
The Coriciden has both 30mg of DXM and 4 mg of CPM, so it's good for killin' 2 birds with one stone. No pun intended.

Also, some people are under the impression that all these drugs make the high "dirty". They CAN, no doubt about it, but in the dosages I listed, there are *NO* perceived changes in the quality of the high. It really does feel like you took more opiate, minus some itching.

Anyway, that's basically it! Hope I manage to help some of you guys out on your voyages to the land of nod, and if you have any questions, feel free to post.

And if this is too lengthy, it's because I'm yakked out of my skull PLUS 48mg hydromorphone; preloaded, of course, with my all-powerful formula.

...and I'm procrastinating for a paper due tomorrow morning. But that's besides the point. Peace!

N0 W4RN1NG

EDIT: Forgot to mention:

This formula should NOT be used in combination with codeine. Codeine's pleasurable effects are largely dependant on it's metabolization into morphine via CYP450 subsets. This formula basically fucks that shit up the ass. If you're using codeine, just take the DXM.

Also, if you plan on drinking alcohol, nix the Aleve. It can cause some nasty damage to your stomach in combo with alcohol. Same goes for APAP\Tylenol(acetaminophen), so if you're taking opiates with tylenol included (Vicoden, Percoset, Endocet, Tylenol 3, etc) be nice to your liver and don't drink. Liver failure is no picnic, mkay?
 #16 
Old 2008-05-26, 21:55
Bink Bink is offline
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Default Re: oxycontin time release removal

Yep, the WHOLE pill is a time release system. Even crushed it still would NOT hit or absorb as fast as ooxy instant release. I believe they call it a wax matrix. It is the same with ms contin. Each molecule of the drug is incased in a wax matrix.

That's crazy shit. I what chemists can do (though I hate this kind of crap getting in the way of a good high).
 
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