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| Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference. |
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#1
 2008-05-10, 04:20
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DiamondX 
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Rima
Wiki says nonreversible MAOIs permanently disable the MAO, but reversible MAOIs only do it temporarily. How can you reverse a reversible MAOI?
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#2
 2008-05-10, 04:48
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thatcoolkid 
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Re: Rima
By reversing a reversible MAOI I hope you mean getting it off the receptor (MAO) ;)
The reversible MAO inhibitors can be displaced from the MAO enzymes by tyramine so that the danger of the so-called "cheese effect" (the heightened risk from tyramine which is often found in aged cheeses, among other foods) is significantly reduced.
http://www.everything2.org/e2node/MAO%2520Inhibitor
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#3
 2008-05-10, 05:01
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DiamondX 
Regular
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Re: Rima
Does this mean RIMAs aren't very dangerous with tyramine, but still just as dangerous as typical MAOIs with drugs?
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#4
 2008-05-10, 05:17
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thatcoolkid 
Regular
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Re: Rima
According to this (http://www.erowid.org/chemicals/maois/maois_info7.shtml) tyramine doesn't seem to be that dangerous w/ RIMAs.
I don't know if I quite understand what you're asking. Mixing MDMA w/ MAOIs is probably more dangerous than using tyramine to displace RIMAs.
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#5
 2008-05-10, 10:25
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DiamondX 
Regular
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Re: Rima
Thanks for the link, you answered my questions.
/thread
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