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| Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference. |
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#1
 2008-04-15, 19:53
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Tolerance: Benzos
hypothetically:
a steady consumption of about 4-5mg of ativan (lorazepam) for the last 4-5 days.
Due to... tolerance feels 4 mg of ativan to a much lesser degree.
besides waiting - is there anything that can be done? Is there a quick way to lower tolerance?
- I know that seems silly, but just wondering if some totsian out there knew some special secret I was unaware of.
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#2
 2008-04-15, 20:00
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Re: Tolerance: Benzos
yeah bro all you have to do is press the button on your gooch that says "lower benzo tolerance"
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#3
 2008-04-15, 21:09
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xxdarksidexx 
Regular
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Re: Tolerance: Benzos
Quote:
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Originally Posted by kwerjack
yeah bro all you have to do is press the button on your gooch that says "lower benzo tolerance"
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LOL FUCKING OWNED.!!! Wean the fuck off man there aint no magic cures.
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#4
 2008-04-15, 22:34
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Regular
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OPS 2A building 688-6911(b)
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Re: Tolerance: Benzos
Wean the fuck off man there aint no magic cures.
For real.
If you could lower your tolerance at will don't you think every addict would be doing this and it'd be really well known?
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#5
 2008-04-16, 00:57
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Time Out Sasquatch 
Regular
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Re: Tolerance: Benzos
Quote:
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Originally Posted by tylerdurdenzs
hypothetically:
a steady consumption of about 4-5mg of ativan (lorazepam) for the last 4-5 days.
Due to... tolerance feels 4 mg of ativan to a much lesser degree.
besides waiting - is there anything that can be done? Is there a quick way to lower tolerance?
- I know that seems silly, but just wondering if some totsian out there knew some special secret I was unaware of.
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Drink grapefruit juice with it. Be careful though.
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#6
 2008-04-16, 01:25
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42Oinchrims 
Regular
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Re: Tolerance: Benzos
Drink grapefruit juice with it. Be careful though.
that only works with diazepam
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#7
 2008-04-16, 01:40
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Time Out Sasquatch 
Regular
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Re: Tolerance: Benzos
that only works with diazepam
Are you sure? Because I thought it applied to all benzo's, and I personally thought it affected the strength of Xanax and ativan. Actaully I'm alost positive that in my mom's little packet they attach to her Xanax script that it specifically mentions not to drink grapefruit juice.
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#8
 2008-04-16, 01:43
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Re: Tolerance: Benzos
that only works with diazepam
you just asking for a link from me?
http://en.wikipedia.org/wiki/CYP3A4#CYP3A4_ligands
http://en.wikipedia.org/wiki/Alprazolam#Food_and_drug_interactions
benzodiazepines are substrates of this enzyme, grapefruit juice is a "strong inhibitor"
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#9
 2008-04-16, 01:51
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Time Out Sasquatch 
Regular
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Re: Tolerance: Benzos
All I know is, that when I was addicted to benzo's physically I could take up to 10 milligrams of xanax and go to work, but if I drank a bottle of grapefruit juice with 2-4 milligrams of xanax that i usually wouldn't remember shit after the last gulp. I'd also usually wake in the shower with the water being ice cold, yet set to hot.
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#10
 2008-04-16, 02:05
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42Oinchrims 
Regular
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Re: Tolerance: Benzos
http://www.mayoclinicproceedings.com/inside.asp?AID=1616&UID=
http://www.med.or.jp/english/pdf/2001_03/136_141.pdf (do ctrl f diazepam)
According to these sites its only diazepam, midazolam, and triazolam(sp?). NOt clonazepam or xanax. I dunno maybe im wrong, ive always thought it was just valium. I never noticed any difference taking xanax and grapefruit juice.
Edit: actually heres the exact same argument. http://www.bluelight.ru/vb/showthread.php?t=139536
you guys are prolly right, if it works for you go for it, it really only worked with valium for me.
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