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Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference.

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 #1 
Old 2008-03-25, 20:52
Dr. Budd Dr. Budd is offline
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Default Opiate Potentiation

So I got a 40mg OC and I kinda want a boost. I got some grapefruit and baking powder. Do I take both of these before or after I drop my OC?

Don't worry I won't die/od or anything, I'm doing this 'cause a 40 is not what I usually take, I usually take a 60 and am trying to compensate for the missing 20.

Your help would be appreciated, thanks.
 #2 
Old 2008-03-25, 20:59
Mr. Binks Mr. Binks is offline
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Default Re: Opiate Potentiation

Up yousa annus?

:)
 #3 
Old 2008-03-25, 21:02
happyonehitter happyonehitter is offline
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Default Re: Opiate Potentiation

To get the ABSOLUTE MOST out of your opiate, try N0 W4RN1NG's patented opioid potentiation formula:

T-45) 600mg Tagamet HB(Cimetidine HCl), a large glass of tonic water (or another source of quinine), and a large glass of (white) Grapefruit juice, preferably from concentrate.
T-35) 30mg DXM HBr, 4mg CPM, 25mg Benadryl(Diphenhydramine HCl), 330mg Naproxen(Aleve).
T-20) 2 Tums OR 1.5 Tbsp. of Baking SODA. (Obviously this step only applies if you are eating your opes)
T-0) Parachute\chew\rail\bang your opiate\opioid.
T+10) Smoke a bowl or two. Not more, you don't want to over power it.

If you want the most out of it, do not snort it - just eat it (highest bioavailability is orally). If you want a quicker onset, parachute it or dissolve it into a shot of water or something.
 #4 
Old 2008-03-25, 21:07
Dr. Budd Dr. Budd is offline
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Default Re: Opiate Potentiation

Thanks man, I appreciate it! Oh... binks, SUCK A DICK! You pathetic teenage, prepubescent, star wars loving twat! :) Have a nice day! :)
 #5 
Old 2008-03-25, 21:21
JustAnotherAsshole JustAnotherAsshole is offline
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Default Re: Opiate Potentiation

Quote:
Originally Posted by Dr. Budd
Thanks man, I appreciate it! Oh... binks, SUCK A DICK! You pathetic teenage, prepubescent, star wars loving twat! :) Have a nice day! :)


Yeah, don't pay attention to that Cunt Binks.
 #6 
Old 2008-03-25, 21:24
the half unlit the half unlit is offline
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Default Re: Opiate Potentiation

Snorting it would really give you that boost your looking for. If so fuck the baking soda and take 25mg-50mg benadryl with grapefruit juice before hand. Smoke a little pot after you do it and youll be happy.

Edit : Oh i just read happyonehitter's post and so im starting to think that way would be better. Ive just always got a certain satisfaction out of snorting my OC.
 #7 
Old 2008-03-25, 21:51
happyonehitter happyonehitter is offline
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Default Re: Opiate Potentiation

Quote:
Originally Posted by the half unlit
Snorting it would really give you that boost your looking for. If so fuck the baking soda and take 25mg-50mg benadryl with grapefruit juice before hand. Smoke a little pot after you do it and youll be happy.

Edit : Oh i just read happyonehitter's post and so im starting to think that way would be better. Ive just always got a certain satisfaction out of snorting my OC.


Snorting any drug is going to hit you quicker than eating it, as it starts getting into your bloodstream pretty much straightaway. This quicker onset is what gives people the impression that snorting makes drugs 'stronger'. However, this quicker onset means that it will not last as long. Taking OC orally will get you higher for longer (but more gradually) than the same amount up the nose, due to its huge oral bioavailability.

It just depends on what the drug in question is. HM, for example, is better snorted than eaten. Morphine sucks both ways, and needs to be slammed or plugged to be halfway decent.
 #8 
Old 2008-03-26, 03:24
Internet-Weed-Dude Internet-Weed-Dude is offline
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Default Re: Opiate Potentiation

Snorting any drug is going to hit you quicker than eating it

WRONG. stop polluting the forums with your mis-information you fucking idiot.
 #9 
Old 2008-03-26, 05:13
Regular
 
Fuckville
Default Re: Opiate Potentiation

A quick search could have prevented this thread from wasting everyone's time.

Cheers.
 #10 
Old 2008-03-26, 08:29
happyonehitter happyonehitter is offline
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Default Re: Opiate Potentiation

WRONG. stop polluting the forums with your mis-information you fucking idiot.

Nasal insufflation is commonly used for many psychoactive drugs because it causes a much faster onset than orally and bioavailability is usually, but not always, higher than orally.

12345
 #11 
Old 2008-03-26, 09:56
Aces N 8S Aces N 8S is offline
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Default Re: Opiate Potentiation

Snorting any drug is going to hit you quicker than eating it, as it starts getting into your bloodstream pretty much straightaway. This quicker onset is what gives people the impression that snorting makes drugs 'stronger'. However, this quicker onset means that it will not last as long. Taking OC orally will get you higher for longer (but more gradually) than the same amount up the nose, due to its huge oral bioavailability.

It just depends on what the drug in question is. HM, for example, is better snorted than eaten. Morphine sucks both ways, and needs to be slammed or plugged to be halfway decent.

does anyone have a reputable source for the rectal v. oral bioavailabilities of morphine?
 #12 
Old 2008-03-26, 10:07
plainclothescop plainclothescop is offline
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Default Re: Opiate Potentiation

does anyone have a reputable source for the rectal v. oral bioavailabilities of morphine?
http://www.springerlink.com/content/m610545w837pm83j/

Click on the "pdf" link.
 #13 
Old 2008-03-26, 15:02
Internet-Weed-Dude Internet-Weed-Dude is offline
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Default Re: Opiate Potentiation

12345

you fucking idiot. your source proves you wrong as well since you said the bioavailability is always higher with insufflating. THAT is what i said was mis-information because it's not always the case.
 #14 
Old 2008-03-26, 16:07
happyonehitter happyonehitter is offline
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Default Re: Opiate Potentiation

you fucking idiot. your source proves you wrong as well since you said the bioavailability is always higher with insufflating. THAT is what i said was mis-information because it's not always the case.

Try reading it properly. I said that the onset is always quicker when snorting, which it is (compared to orally). However, the bioavailability of each ROA is going to depend upon the drug in question.
 
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