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Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference.

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 #1 
Old 2008-03-23, 16:08
Regular
 
the Cities of the Future
Default Oxycodone/APAP CWE

I know how do to the cold water extraction on the pills, but what is the most efficient way to evaporate the water so you can rail the oxy?

I searched "CWE" in the forum but nothing came up because apparently the query was too common/not long enough.
 #2 
Old 2008-03-23, 16:13
Super Moderator
 
Sebastopol CA
Default Re: Oxycodone/APAP CWE

Put the liquid in a glass pie plate or something like that. Then put it in an oven set to no more than 200-250 degrees F.
 #3 
Old 2008-03-23, 16:15
Regular
 
the Cities of the Future
Default Re: Oxycodone/APAP CWE

Thanks Meta,

but how long does that take?

Would a microwave be quicker/work or would it be too much and destroy or at least degrade it?
 #4 
Old 2008-03-23, 18:05
Super Moderator
 
Sebastopol CA
Default Re: Oxycodone/APAP CWE

Quote:
Originally Posted by the_chad
Thanks Meta,

but how long does that take?

Would a microwave be quicker/work or would it be too much and destroy or at least degrade it?


It takes about 15 20 minutes. And no, don't use a microwave. You want the dry heat of an oven.
 #5 
Old 2008-03-24, 16:30
odysseybmx414 odysseybmx414 is offline
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Default Re: Oxycodone/APAP CWE

say i was extracting the oxycodone out of 21 7.5/325's that would give me 157.5mg of oxy. i do not have a mg scale, how would i measure dose? i want the powder, not the liquid, so i will be evaporating. i like 15mg/20mg doses. i could also just eat the fucking pills, but i am not a fan of apap.
 #6 
Old 2008-03-24, 17:24
happyonehitter happyonehitter is offline
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Default Re: Oxycodone/APAP CWE

Quote:
Originally Posted by odysseybmx414
say i was extracting the oxycodone out of 21 7.5/325's that would give me 157.5mg of oxy. i do not have a mg scale, how would i measure dose? i want the powder, not the liquid, so i will be evaporating. i like 15mg/20mg doses. i could also just eat the fucking pills, but i am not a fan of apap.


1) You're not going to extract perfectly, so there will not be 157.5mg OC.
2) The total APAP is 6.825g - not even lethal if taken all at once (which it won't be).
3) You don't have the equipment to do a clean extraction (i.e. all APAP removed), or dose out the OC accurately.

1+2+3 = Just eat the pills and enjoy.
 #7 
Old 2008-03-24, 17:29
Regular
 
OPS 2A building 688-6911(b)
Default Re: Oxycodone/APAP CWE

^ Yea, a CWE is only really necessary if taking over 8,000mg of APAP at once, or you're repeatedly taking high doses [eg 4,000mg a day or more a few times a week].
 #8 
Old 2008-03-24, 17:38
Von Bass Von Bass is offline
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Default Re: Oxycodone/APAP CWE

Quote:
Originally Posted by odysseybmx414
say i was extracting the oxycodone out of 21 7.5/325's that would give me 157.5mg of oxy. i do not have a mg scale, how would i measure dose? i want the powder, not the liquid, so i will be evaporating. i like 15mg/20mg doses. i could also just eat the fucking pills, but i am not a fan of apap.


1.) measure quantity of liquid - e.g. 50ml
2.) calculate mg/ml - assume a perfect extraction to avoid overdose - e.g. 157.5 / 50 = 3.15mg/ml
3.) multiply doses out - you want 15 - 20mg, that's approximately 5ml per dose.
4.) evaporate doses separately. 5ml does not take long to evaporate, and can be measured easily with a pipette.
 #9 
Old 2008-03-24, 23:03
odysseybmx414 odysseybmx414 is offline
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Default Re: Oxycodone/APAP CWE

thank you i appreciate your opinions
 #10 
Old 2008-03-24, 23:10
pharmaceuticalfunk pharmaceuticalfunk is offline
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Default Re: Oxycodone/APAP CWE

You can also use a hairdryer to evaporate the water. But, I just rail them with APAP, it has a barely noticeable burn and still works effectively. In fact some of the information I have read indicates that the drug may be slightly more potent with the APAP
 #11 
Old 2008-03-24, 23:19
odysseybmx414 odysseybmx414 is offline
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Default Re: Oxycodone/APAP CWE

yeah well i would imagine that apap isn't to healthy for the nasal cavities.
 #12 
Old 2008-03-25, 02:09
Aces N 8S Aces N 8S is offline
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Default Re: Oxycodone/APAP CWE

also the excessive powder in your nose can coat your mucus memmbranes with APAP and block the oxy from being absorbed.

besides, oxy has a much higher bioavailability orally than intranasally.

just eat the damn pills
 #13 
Old 2008-03-25, 07:25
Regular
 
the Cities of the Future
Default Re: Oxycodone/APAP CWE

I've said it like three times now, but

DO AN ENEMA

It is much more effective than railing them or eating them.

I'm completely serious, it makes it feel like you've done 150% than you've actually done.

And, you don't have to evaporate the water, just take the water and put it all in a big (not too big:p) syringe and send it up the back door.
 #14 
Old 2008-03-25, 10:23
Aces N 8S Aces N 8S is offline
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Default Re: Oxycodone/APAP CWE

Quote:
Originally Posted by the_chad
I've said it like three times now, but

DO AN ENEMA

It is much more effective than railing them or eating them.

I'm completely serious, it makes it feel like you've done 150% than you've actually done.

And, you don't have to evaporate the water, just take the water and put it all in a big (not too big:p) syringe and send it up the back door.


Uh, no.

rectal bioavailability for oxycodone is about 61% while oral bioavailability is between 60% and 87%. so that "extra high" you're feeling is absolutely pure placebo.

stop reccomendng that everyone shove every drug up their ass. every drug has different bioavailabilities for each ROA and very often rectal administration is not the most effecient.

go ahead and shove any drug you want up your own ass, but please, while you're down there anyway, pull your head out and do some research before you go around spouting ignorance.
 #15 
Old 2008-03-25, 10:56
Regular
 
the Cities of the Future
Default Re: Oxycodone/APAP CWE

Uh, no.

rectal bioavailability for oxycodone is about 61% while oral bioavailability is between 60% and 87%. so that "extra high" you're feeling is absolutely pure placebo.

stop reccomendng that everyone shove every drug up their ass. every drug has different bioavailabilities for each ROA and very often rectal administration is not the most effecient.

go ahead and shove any drug you want up your own ass, but please, while you're down there anyway, pull your head out and do some research before you go around spouting ignorance.

Everybody on bltc has always posted that its much more efficient to do this.

Show me proof that the rectal bioavailability is less than oral.

I know the difference between placebo and actual, so don't give me that bullshit.

And I've only ever recommended it for oxy, so whats this about EVERY drug?
 #16 
Old 2008-03-25, 11:10
happyonehitter happyonehitter is offline
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Default Re: Oxycodone/APAP CWE

Everybody on bltc has always posted that its much more efficient to do this. I know the difference between placebo and actual, so don't give me that bullshit.

No-one has posted that it's more efficient. It depends on the drug in question. As OC's oral bioavailability is so damn high anyway, theres no point in shoving it up your arse. Morphine on the other hand has terrible oral and intranasal bioavailabilities, so it is more efficient to plug it. Also, the reason plugging feels like you have done more than you actually have is because it hits you a lot quicker (5 mins).
 #17 
Old 2008-03-25, 11:12
Regular
 
the Cities of the Future
Default Re: Oxycodone/APAP CWE

No-one has posted that it's more efficient.

I'm talking about in other threads man.

The bioavailability of oral administration averages 60-87%, with rectal administration yielding the same results.

http://en.wikipedia.org/wiki/Oxycodone


Its the same, and possibly higher in the rectum, so therefore I am partially right, and you are partially, right, because everybody is unique.
 #18 
Old 2008-03-25, 11:22
Aces N 8S Aces N 8S is offline
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Default Re: Oxycodone/APAP CWE

http://books.google.com/books?id=BK0WduGnx2kC&pg=PA131&lpg=PA131&dq=oxycodone+rectal+bioavailability&source=web&ots=yVsovuTqU5&sig=_kQpNdCNRkkdMQNNXhCyhRMlddU&hl=en#PPP1,M1

book on cancer pain treatments.

61% rectal bioavailability.

60-87% oral.

so the mean is higher with oral, and even if you call the difference negligible then an enema is a lot of unnecessary work and discomfort.

so no, we're not both right. you were wrong to suggest rectal administration, and i was right to point out that you were wrong. deal with it.
 #19 
Old 2008-03-25, 16:20
odysseybmx414 odysseybmx414 is offline
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Default Re: Oxycodone/APAP CWE

i just wanted to snort the oxycodone without the apap. i would rather snort 15 mg of powder than 0.5g of powder and only get 7.5 mg of oc. and yes i weighed the pill on a gram scale. why the fuck would anyone want to snort 325mg of apap, 7.5mg of oc, and 167.5mg of fucking binders. and no i do not want to plug the shit. i don't find the idea of using my anus everytime i want to get high appealing.
 #20 
Old 2008-03-25, 16:47
Regular
 
the Cities of the Future
Default Re: Oxycodone/APAP CWE

Quote:
Originally Posted by Aces N 8S
http://books.google.com/books?id=BK0WduGnx2kC&pg=PA131&lpg=PA131&dq=oxycodone+rectal+bioavailability&source=web&ots=yVsovuTqU5&sig=_kQpNdCNRkkdMQNNXhCyhRMlddU&hl=en#PPP1,M1

book on cancer pain treatments.

61% rectal bioavailability.

60-87% oral.

so the mean is higher with oral, and even if you call the difference negligible then an enema is a lot of unnecessary work and discomfort.

so no, we're not both right. you were wrong to suggest rectal administration, and i was right to point out that you were wrong. deal with it.


Whatever you say.

I just know that when I administer it rectally, I get much more stronger effects than when I chew them.

End of story.
 #21 
Old 2008-03-25, 16:49
happyonehitter happyonehitter is offline
Regular
 
Default Re: Oxycodone/APAP CWE

Quote:
Originally Posted by odysseybmx414
i just wanted to snort the oxycodone without the apap. i would rather snort 15 mg of powder than 0.5g of powder and only get 7.5 mg of oc. and yes i weighed the pill on a gram scale. why the fuck would anyone want to snort 325mg of apap, 7.5mg of oc, and 167.5mg of fucking binders. and no i do not want to plug the shit. i don't find the idea of using my anus everytime i want to get high appealing.


Dude, just eat them. You're gonna get more out of them by eating. Why do all the kidiots have a fucking obsession with snorting anything and everything, even if it's less efficient? Hydromorphone on the other hand has a greater bioavailability nasally than orally, so snort away by all means, but oxy is more efficient by mouth!
 #22 
Old 2008-03-25, 18:27
JustAnotherAsshole JustAnotherAsshole is offline
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Default Re: Oxycodone/APAP CWE

In fact some of the information I have read indicates that the drug may be slightly more potent with the APAP

They mean for pain reduction. it makes sense that snorting the APAP WITH the oxy would make it more potent, but you wont feel a stronger high.

Anyway, like you said in the rest of your post, the APAP doesn't burn much, and it is barely noticeable.
__________________________________________________ ________________
but oxy is more efficient by mouth!

Now that, I didn't know. You'd think it'd be more available by snorting....
ANYWAY: I learned something today. Thank you totse! ^^
 #23 
Old 2008-03-25, 21:35
odysseybmx414 odysseybmx414 is offline
Regular
 
Default Re: Oxycodone/APAP CWE

haha i have been just eating the fucking pills i jsut thought i would explain why i dont thing snorting all that shit is worth it.
i dont understand the obsession with snorting either i just wanted pure oxycodone.

bottom line thread is no longer useful, and can be locked. unless you guys want to continue arguing wheter the anus or mouth is better at swallowing pills
 #24 
Old 2008-03-28, 10:39
Regular
 
the Cities of the Future
Default Re: Oxycodone/APAP CWE

No I think I'm done.

And you don't need to close a thread just because the topic is finished, only if it's a bullshit topic.
 
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