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| Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference. |
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#1
 2008-03-22, 03:01
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cyka 
Regular
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Lsd
I'm tripping and it got me thinking (as acid does)
What the fuck is LSD? I don't mean the chemical makeup, but what are its actual effects on consciousness and human senses? I heard that it opens/adjusts them to the extent that we sense stuff that is there, but that our senses cannot usually detect. Is this about right? I just think it's a damn weird drug. In a good way.
Peace
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#2
 2008-03-22, 03:10
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ime 
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Re: Lsd
I always say it "makes things more and open...vulnerable to our study and opinion"
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#3
 2008-03-22, 03:12
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cyka 
Regular
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Re: Lsd
that's definitely true. I'm just wondering if
a)what I heard is true
b) anyone else knows anything interesting about it
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#4
 2008-03-22, 03:22
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Chemical Eudaemonia 
Regular
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Re: Lsd
Research in the 1970s showed that LSD temporarily suppresses the firing of serotonin- releasing neurons of the raphe nuclei (Rechs & Rosecrans, 1982), a part of the brainstem reticular activating system. These neurons send axons into widespread regions of the cerebral cortex and limbic system, where they release serotonin when active. Because the raphe nuclei also go silent during REM sleep, the notion that the psychedelic state represents dreaming while awake became the standard account. However, subsequent research contradicted this interpretation by showing that LSD and other psychedelics act postsynaptically as agonists at 5-HT2 Homosapiens is the only species that will voluntarily take a psychadelic drug again after experiencing its effect receptors (Jacobs, 1987), the most common serotonin receptors in the brain. The silencing of the raphe nuclei was due to LSDs agonist action at presynaptic autoreceptors (inhibitory 5-HT1) on the serotonin-releasing cells. Autoreceptors serve a negative feedback function such that the neurotransmitter (in this case serotonin) inhibits its own release when extracellular levels are too high. LSD thus acts like serotonin both presynaptically and postsynaptically, inhibiting serotonin release via inhibitory 5- HT1 autoreceptors while simultaneously activating excitatory postsynaptic 5-HT2 receptors; only the latter action is relevant to the psychedelic state (Feldman, Meyer & Quenzer, 1997). This interpretation was bolstered by the finding that serotonin antagonists can block psychedelic effects. Recent PET scans of volunteers under the influence of psilocybin showed hyperactivity of the frontal and occipital lobes, especially in the right hemisphere, presumably reflecting strong activation of excitatory 5-HT2 receptors in the cortex (Vollenweider et al., 1997).
http://sci-con.org/2003/06/the-neurochemistry-of-psychdelic-experiences/
LSD does not give you super senses
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#5
 2008-03-22, 03:29
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cyka 
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Re: Lsd
Disappointing. Cheers for the link though, that's interesting.
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#6
 2008-03-22, 03:43
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Regular
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the Cities of the Future
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Re: Lsd
Do you hallucinate on LSD (personally)?
I know its supposed to make you hallucinate, but after even taking up to 5 hits, I've only had one single hallucination.
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#7
 2008-03-22, 03:49
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Re: Lsd
You clearly have some weak acid. You wouldn't be able to type an intelligible sentence on some real acid.
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#8
 2008-03-22, 03:55
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plainclothescop 
Regular
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Re: Lsd
Quote:
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Originally Posted by the_chad
Do you hallucinate on LSD (personally)?
I know its supposed to make you hallucinate, but after even taking up to 5 hits, I've only had one single hallucination.
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You're buying pathetically poor-quality acid then.
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#9
 2008-03-22, 04:23
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Krees 
Regular
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Re: Lsd
Quote:
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Originally Posted by the_chad
Do you hallucinate on LSD (personally)?
I know its supposed to make you hallucinate, but after even taking up to 5 hits, I've only had one single hallucination.
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Maybe you were eating breath mints.
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#10
 2008-03-22, 04:27
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Re: Lsd
You clearly have some weak acid.
True.
You wouldn't be able to type an intelligible sentence on some real acid.
Not necessarily true. I've typed/written some pretty interesting shit when tripping face :)
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#11
 2008-03-22, 07:05
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Ave2 
Regular
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Re: Lsd
Quote:
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Originally Posted by Chemical Eudaemonia
Research in the 1970s showed that LSD temporarily suppresses the firing of serotonin- releasing neurons of the raphe nuclei (Rechs & Rosecrans, 1982), a part of the brainstem reticular activating system. These neurons send axons into widespread regions of the cerebral cortex and limbic system, where they release serotonin when active. Because the raphe nuclei also go silent during REM sleep, the notion that the psychedelic state represents dreaming while awake became the standard account. However, subsequent research contradicted this interpretation by showing that LSD and other psychedelics act postsynaptically as agonists at 5-HT2 Homosapiens is the only species that will voluntarily take a psychadelic drug again after experiencing its effect receptors (Jacobs, 1987), the most common serotonin receptors in the brain. The silencing of the raphe nuclei was due to LSDs agonist action at presynaptic autoreceptors (inhibitory 5-HT1) on the serotonin-releasing cells. Autoreceptors serve a negative feedback function such that the neurotransmitter (in this case serotonin) inhibits its own release when extracellular levels are too high. LSD thus acts like serotonin both presynaptically and postsynaptically, inhibiting serotonin release via inhibitory 5- HT1 autoreceptors while simultaneously activating excitatory postsynaptic 5-HT2 receptors; only the latter action is relevant to the psychedelic state (Feldman, Meyer & Quenzer, 1997). This interpretation was bolstered by the finding that serotonin antagonists can block psychedelic effects. Recent PET scans of volunteers under the influence of psilocybin showed hyperactivity of the frontal and occipital lobes, especially in the right hemisphere, presumably reflecting strong activation of excitatory 5-HT2 receptors in the cortex (Vollenweider et al., 1997).
http://sci-con.org/2003/06/the-neurochemistry-of-psychdelic-experiences/
LSD does not give you super senses
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do alterations to the 5-HT2 persist after LSD use?
I would assume so...a few people i know who used LSD quite a few times years ago are on Seritonin reuptake inhibitors to help with "brought out" mania, depression ect....
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#12
 2008-03-22, 07:26
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doornob_lightbulb 
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Re: Lsd
Quote:
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Originally Posted by the_chad
Do you hallucinate on LSD (personally)?
I know its supposed to make you hallucinate, but after even taking up to 5 hits, I've only had one single hallucination.
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the chad is getting ripped the fuck off. Badly.
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#13
 2008-03-22, 10:34
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42Oinchrims 
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Re: Lsd
Were you taking paper or a liquid or was it dropped it on something else. Cuz like everyone said u got jipped.
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#14
 2008-03-22, 14:47
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jellyfish 
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Re: Lsd
Whether or not you got visuals is not at all an indication of whether it was real acid or not. Some people just don't get them or need really high doses to get them. Did the 5 hits still fuck you up?
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#15
 2008-03-22, 20:07
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Re: Lsd
Quote:
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Originally Posted by the_chad
Do you hallucinate on LSD (personally)?
I know its supposed to make you hallucinate, but after even taking up to 5 hits, I've only had one single hallucination.
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its all up to your definition of a hallucination. some people will say: any general distortion of the senses (which i get when i smoke weed)
what you might think is an out of body experience, for example being an alien on mars.
the first one will most likely happen unless you take a ridiculously low dose of shit acid.
the second will most likely not happen unless you take a great amount.
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#16
 2008-03-23, 02:25
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Drug-Demon 
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Re: Lsd
LSD is the shit. I hope to God to be getting some in the next couple days (really potent liquid)!
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#17
 2008-03-23, 02:50
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Ave2 
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Re: Lsd
Quote:
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Originally Posted by Drug-Demon
LSD is the shit. I hope to God to be getting some in the next couple days (really potent liquid)!
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Nobody cares.
As far as LSD and expanding your mind.....you have absolutely nothing to expand.
Also note your fucking posts piss me off, ever since you started posting.
Particularly because you idolize drug addicts, and have previously stated that one day you wish to try heroin and then proceed to inject it.
Ohduude ur so hardcor on teh interwebz.
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#18
 2008-03-23, 05:06
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Regular
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the Cities of the Future
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Re: Lsd
its all up to your definition of a hallucination. some people will say: any general distortion of the senses.
what you might think is an out of body experience, for example being an alien on mars.
the first one will most likely happen unless you take a ridiculously low dose of shit acid.
the second will most likely not happen unless you take a great amount.
Its good acid though
I got fucked out of my head, and the one hallucination I had was pretty damn trippy, but not like all the stories I hear.
I just have a big tolerance to all drugs.
My friend had some molly, he got really damn high off it but when I did the same amount, I just got kind of happy.
Same thing with the acid, my friend did 5 hits and couldn't tell if his eyes were opened or closed, but I just had some very intense trails and that once hallucination (I looked at poster and it started to swirl crazily).
Oh and DXM. Even my first time taking 900mgs I only got a really high 1st.
Some people just don't absorb drugs as much as others do.
The really bad part about the acid though, is that they were 10$ a hit cause they were supposed to be so good.
My buddy got fucked and hallucinated like crazy, and I got fucked, but didn't hallucinate like crazy.
I guess I just need to take like 25 hits some time just to unlock whatever is being held back, I dunno.
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#19
 2008-03-23, 05:51
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dexingsmotpoker 
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Re: Lsd
Oh and DXM. Even my first time taking 900mgs I only got a really high 1st.
S
You're either full of shit or you have no idea what each plateau is like. Or If I remember reading your trip analysis, you didn't even hold in the syrup the entire time, thus, you didn't actually absorb 900 Mg's, therefore you have no room to add that into your list of seemingly high drug tolerances.
Anyway, I'm not going to pretend that I am any sort of brain chemist or anything, and I actually have never been blessed with the chance to do any LSD, but I do remember specifically reading something about how it functioned inside of the brain.
I believe that the certain enzymes or what have you that are dispersed from receptor to receptor in order to determine your sensory input can have their paths mucked with. IE: The enzymes responsible for showing sight will end up in the Odor receptor, etc. This would allow for a (supposedly) common occurance in the LSD trip which is to Smell sound, hear colors, taste music, etc.
This is coming from someone that hasn't actually done LSD yet, so damn.
I really want some though, its at the top of my to do list.
The problem is that it only comes to my small isolated town once every year or five or six months at most, and when it does, it goes for something ridiculous like 25-30 bucks a hit.
If I had an excellent hook up I would probably be able to find some for 15 bucks a hit.
Alright....
/rant
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#20
 2008-03-23, 06:25
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Regular
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the Cities of the Future
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Re: Lsd
You're either full of shit or you have no idea what each plateau is like. Or If I remember reading your trip analysis, you didn't even hold in the syrup the entire time, thus, you didn't actually absorb 900 Mg's, therefore you have no room to add that into your list of seemingly high drug tolerances.
Anyway, I'm not going to pretend that I am any sort of brain chemist or anything, and I actually have never been blessed with the chance to do any LSD, but I do remember specifically reading something about how it functioned inside of the brain.
I believe that the certain enzymes or what have you that are dispersed from receptor to receptor in order to determine your sensory input can have their paths mucked with. IE: The enzymes responsible for showing sight will end up in the Odor receptor, etc. This would allow for a (supposedly) common occurance in the LSD trip which is to Smell sound, hear colors, taste music, etc.
This is coming from someone that hasn't actually done LSD yet, so damn.
I really want some though, its at the top of my to do list.
The problem is that it only comes to my small isolated town once every year or five or six months at most, and when it does, it goes for something ridiculous like 25-30 bucks a hit.
If I had an excellent hook up I would probably be able to find some for 15 bucks a hit.
Alright....
/rant
Thats a different guy dude
read the DXM thread again
I, unlike him, have experienced each plateau and know what they are like. I took robogels, not syrup.
I just had a really high tolerance from doing many 40 robogels, so it IS plausible.
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#21
 2008-03-23, 06:56
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Re: Lsd
I guess I just need to take like 25 hits some time just to unlock whatever is being held back, I dunno.
Hahahaha. Go for it buddy. Good luck.
How can you be sure it's good acid? Just because your friend was 'tripping face' doesn't mean anything if you guys are relatively inexperienced to the whole thing.
By the way, the poster 'swirling' and light trails are the most common visuals one gets one relatively low doses of LSD. Your description leads me to believe the tabs weren't as strong as you'd like to believe.
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#22
 2008-03-23, 07:07
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Regular
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the Cities of the Future
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Re: Lsd
Hahahaha. Go for it buddy. Good luck.
How can you be sure it's good acid? Just because your friend was 'tripping face' doesn't mean anything if you guys are relatively inexperienced to the whole thing.
By the way, the poster 'swirling' and light trails are the most common visuals one gets one relatively low doses of LSD. Your description leads me to believe the tabs weren't as strong as you'd like to believe.
You're probably right.
I am relatively experienced when it comes to psychedelics, however. I've done up to 1620mgs of DXM (chewed up secrets and didn't vomit because I was gone by the time by body would even contemplate being sick), done ketamine and ate 3/8ths of mushrooms once.
I guess that just proves to me that even though I did feel pretty high off low doses of acid, it shows that the true virtue and nature of the drug is much stronger than I've been lead to believe. I just wish I could find a dealer that wouldn't rip me off and actually get some GOOD acid. I can't wait till the first time I discover what a real acid trip is all about.
I was completely serious about the 25 hits of the shitty acid, though.
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#23
 2008-03-23, 16:18
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Regular
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the Cities of the Future
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Re: Lsd
Does LSD and DXM/Ketamine have a cross-tolerance with each other?
I had done both within 24 hours of taking the acid, so that might make a difference.
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#24
 2008-03-23, 17:04
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Re: Lsd
no lsd and dissociatives dont have a cross-tolerance.
and by the way, trail ARE A HALLUCINATION, like i said before, its all up to your definition of hallucination.
and dexingsmotpoker (or whatever) that was completely irrelevant.
only things i could think of are...
Do you take a sri?
maybe theres something wrong with you 5-HT 2a receptor?
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#25
 2008-03-23, 17:13
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Regular
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the Cities of the Future
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Re: Lsd
Quote:
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Originally Posted by kwerjack
no lsd and dissociatives dont have a cross-tolerance.
and by the way, trail ARE A HALLUCINATION, like i said before, its all up to your definition of hallucination.
and dexingsmotpoker (or whatever) that was completely irrelevant.
only things i could think of are...
Do you take a sri?
maybe theres something wrong with you 5-HT 2a receptor?
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No medications whatsoever.
I haven't done acid that many times, only 5
Around the first ten times I ever smoked weed, I didn't get high at all. But then the very first time it actually worked, HOLY SHIT.
Do you think it might have something to do with this and that I just need to keep on trying until I get that breakthrough?
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#26
 2008-03-23, 18:30
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Re: Lsd
You'll break through once you get some quality doses.
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#27
 2008-03-23, 18:34
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Regular
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the Cities of the Future
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Re: Lsd
You've already made your point, there's no need to push it.
Can you explain why I didn't get high the first couple of times I smoked weed, but then suddenly when I smoked the very same weed I was flying?
Isn't it plausible that its the same sort of thing with LSD?
Yes, very much so.
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#28
 2008-03-23, 21:17
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Re: Lsd
Quote:
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Originally Posted by the_chad
You've already made your point, there's no need to push it.
Can you explain why I didn't get high the first couple of times I smoked weed, but then suddenly when I smoked the very same weed I was flying?
Isn't it plausible that its the same sort of thing with LSD?
Yes, very much so.
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Not at all. There's a technique to smoking weed that most people just don't pull off their first time (or first few times) they smoke weed, such as properly inhaling.
However, taking acid is taking acid. All there is to it. There's no way you can improperly put it in your mouth.
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#29
 2008-03-23, 21:25
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throopguy21 
Regular
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Re: Lsd
okay... you're tripping and posting on totse? bullshit, you must not be tripping hard at all. when i'm tripping hard enough to make those kind of realizations i cant even remember it long enough to say it. BLTC doesn't need anymore people like you. Thats a good question you bring up but you dont have to be pretensous(sp?) and shitty.
I think that it opens up your mind and sort of breaks down the barriers to our conciousness that have been under construction since the day we were born. Sub-conciously we censor our thinking and acid and high doses of mushroom, and really any psychadelic in general does this. This i read on a piece of paper after a particularly intense acid trip with a few friends.
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#30
 2008-03-23, 21:43
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Re: Lsd
Quote:
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Originally Posted by the_chad
You've already made your point, there's no need to push it.
Can you explain why I didn't get high the first couple of times I smoked weed, but then suddenly when I smoked the very same weed I was flying?
Isn't it plausible that its the same sort of thing with LSD?
Yes, very much so.
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ahhh, you were probably smoking it wrong, thats why you didnt get high. happened to me too im like what the fuck.
that got me thinking your doing the acid wrong. was it blotter paper? how long did you hold it under your tounge?
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#31
 2008-03-23, 21:46
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Re: Lsd
that got me thinking your doing the acid wrong. was it blotter paper? how long did you hold it under your tounge?
Even if you swallow it right away you're going to trip.
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#32
 2008-03-23, 21:47
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Re: Lsd
Even if you swallow it right away you're going to trip.
no.. it happened to my cousin. waste of 20 dollars
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#33
 2008-03-23, 21:48
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Internet-Weed-Dude 
Regular
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Re: Lsd
the first time i took acid (3 hits) it was very high quality and it blew my mind. I literally wouldn't have been able to type this sentence. i remember going near my computer and the screen was bending in dimensions i cant even describe and it felt like i was sitting sideways or something.
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#34
 2008-03-23, 21:55
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Re: Lsd
no.. it happened to my cousin. waste of 20 dollars
So I guess all those trips I had were placebo...
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#35
 2008-03-23, 22:00
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Re: Lsd
So I guess all those trips I had were placebo...
shut up.
dont flame, just shut up. you CAN do it wrong
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#36
 2008-03-23, 22:03
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Re: Lsd
I'm not flaming. I'm trying to correct all the stupid fucking bullshit in this thread. I've tripped enough times to know what the hell I'm talking about.
Fuck, I've lost faith in BLTC.
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#37
 2008-03-23, 22:04
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Re: Lsd
Quote:
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Originally Posted by Darkus
I'm not flaming. I'm trying to correct all the stupid fucking bullshit in this thread. I've tripped enough times to know what the hell I'm talking about.
Fuck, I've lost faith in BLTC.
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i didnt say you did, i just thought you were going to.
this isnt bullshit. must we consult stupid noob, joe pedo, or meta for all our problems?
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#38
 2008-03-23, 22:06
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Regular
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the Cities of the Future
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Re: Lsd
ahhh, you were probably smoking it wrong, thats why you didnt get high. happened to me too im like what the fuck.
that got me thinking your doing the acid wrong. was it blotter paper? how long did you hold it under your tounge?
Yeah it was blotter paper. I held it under my tongue for 2 hours, then chewed it up and swallowed it.
And I smoked weed properly after the first time. My sister's boyfriend is/was a huge stoner and he got me into it and taught me how to do it after he saw me doing it wrong. After that I took massive rips off bowls and held it in as long as I could, but it still didn't work. It was only when I decided to smoke a joint to meself that it finally worked. So its gotta be something else.
It doesn't even matter. My time will come when it is right.
Darkus, flaming is so pointless, especially for someone who claims to have experienced the wonder of acid. You should know better.
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#39
 2008-03-23, 22:13
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Re: Lsd
Like I said, I'm not flaming, I'm trying to inform the misinformed.
kwerjack, perhaps you should read these:
http://www.erowid.org/ask/ask.php?ID=2874
http://www.drugs-plaza.com/forums/viewtopic.php?t=1072091&highlight=&sid=523aacaffc84cb9965bfaa9802f089d0
Change your mind yet?
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#40
 2008-03-23, 22:17
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Regular
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the Cities of the Future
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Re: Lsd
Like I said, I'm not flaming, I'm trying to correct the bullshit.
kwerjack, perhaps you should read this:
http://www.erowid.org/ask/ask.php?ID=2874
You can post all the links you want.
Every single person is unique and reacts differently to each drug, it says that right on the website.
And flaming isn't just insulting people, its the manner you speak in... Or type, rather.
Perhaps I'm just reading your posts in the wrong sense, but it SOUNDS like you're trying to prove to everyone that you are smarter and know much more, and you're doing it in a shitty tone. Coincides with flaming.
If you are actually trying to help, then I apologize, I just know that I may or may not have a tolerance to LSD, and even though they may or may not have been quality LSD hits, my tripmates had intense hallucinations, and I didn't. So unless they were bullshitting me (possible, but unlikely), something is amiss here.
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#41
 2008-03-23, 22:21
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Re: Lsd
You can post all the links you want.
Every single person is unique and reacts differently to each drug, it says that right on the website.
And flaming isn't just insulting people, its the manner you speak in... Or type, rather.
Perhaps I'm just reading your posts in the wrong sense, but it SOUNDS like you're trying to prove to everyone that you are smarter and know much more, and you're doing it in a shitty tone. Coincides with flaming.
If you are actually trying to help, then I apologize, I just know that I may or may not have a tolerance to LSD, and even though they may or may not have been quality LSD hits, my tripmates had intense hallucinations, and I didn't. So unless they were bullshitting me (possible, but unlikely), something is amiss here.
I know for a FACT I'm not smarter than a lot of people on this board, I just might happen to know a little more about acid than psychedelic amateurs.
And I'm not trying to "get a 'tude" with any of you, I just don't like when misinformation is being spread. I'm trying to tell you from first hand experiences that swallowing acid is NOT a waste. Holding it under your tongue simply absorbs it at a slightly faster rate.
By the way, Internet 101 says you should never try to apply a certain 'tone' to things you read.
Just curious, how many times have the people you dosed with tripped acid?
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#42
 2008-03-23, 22:33
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Regular
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the Cities of the Future
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Re: Lsd
I know for a FACT I'm not smarter than a lot of people on this board, I just might happen to know a little more about acid than psychedelic amateurs.
And I'm not trying to "get a 'tude" with any of you, I just don't like when misinformation is being spread. I'm trying to tell you from first hand experiences that swallowing acid is NOT a waste. Holding it under your tongue simply absorbs it at a slightly faster rate.
By the way, Internet 101 says you should never try to apply a certain 'tone' to things you read.
Just curious, how many times have the people you dosed with tripped acid?
Honestly?
The dealer who sold it to me is once of the people I tripped with. He's 19 and has had a TON of experience.
The other people were just my other *amateur* friends as you so bluntly put it, who hadn't touched another drug except weed.
The dealer has done it at least 50 times, the same acid that he sold me. We go back quite aways, and are quite close. He is a friend first, and a dealer second. So he has no reason to lie to me just to sell me shitty acid.
He said he hallucinated off the same amount I did, and I believe him, I have no reason not to. He didn't trip as hard as my other friends did, but tripped harder than I did.
He has sold me ounces of mushrooms, all of which I experienced the stereotypical mushroom hallucinations and trips, all of which I had a very good time on.
I am more positive than not that it was good acid, so it must be something with my body and mind.
Anyways, I don't need to prove anything to you, but if you're that intent on your point, then I will give you my address and you can send me what you think is good acid, and if you're right, I will send you a strong apology. and fifty bucks because I've been wrong.
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#43
 2008-03-24, 01:35
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OzzBozz 
Regular
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Re: Lsd
i've noticed an increase in LSD availability locally.... possibly, its because I am in with the right circle now in comparison to when i wasn't.
either way, i took a half tab of some very well-dosed clean blotter last night on top of 6 rolls.... i guess, a mild CANDY flip... i got some nice visuals, concrete melting etc. definately a nice touch on top of some MDMA and MDA.
personally, i love LSD. after you fry, you always reflect back on your experience with great approval ( or dissaproval ). with other drugs such as coke, your just like... "yep, i got really coked out"
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#44
 2008-03-24, 02:33
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Re: Lsd
personally, i love LSD. after you fry, you always reflect back on your experience with great approval ( or dissaproval ). with other drugs such as coke, your just like... "yep, i got really coked out"
that's because LSD positively changes your life and perception on certain aspects of it.
coke, on the other hand...
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#45
 2008-03-24, 03:30
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Chemical Eudaemonia 
Regular
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Re: Lsd
coke pwns LSD
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#46
 2008-03-24, 03:38
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Re: Lsd
coke pwns LSD
psshh...coke sucks ass, as does meth, and crack, and heroin, and anything else with a shitty scene
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#47
 2008-03-24, 04:07
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Internet-Weed-Dude 
Regular
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Re: Lsd
psshh...coke sucks ass, as does meth, and crack, and heroin, and anything else with a shitty scene
it's the people that make the shitty scene out of the drug that suck ass.
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#48
 2008-03-24, 04:08
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Internet-Weed-Dude 
Regular
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Re: Lsd
that's because LSD positively changes your life and perception on certain aspects of it.
one sided opinion.
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