I am bipolar and taking a couple medications but don't want to have to cut off entheogen use if at all possible (though I certainly will if it is the responsible thing to do due to the dangers of drug contraindications). I am on 75mg Lamictal and 30mg Cymbalta. I have done just about everything with the Lamictal and have't had any problems nor did I hear of any in my pre-use research. However, Cymbalta is a different story. I am interested if there would be an interaction between it and tryptamine compounds (DMT , psilocybin/psilocin, etc.) or LSD--in short, with other serotogenic drugs with which an SNRI or SSRI might interact.

I understand that Cymbalta is an SNRI, which shouldn't cause problems as far as I can tell, but someone has told me that it is an SSRI as well and I know that taking SSRIs with any serotogenic compounds, among which are the included tryptamines and LSD, is dangerous in that it could instigate Serotonin Syndrome. I can't confirm that Cymbalta is an SSRI in addition to an SNRI from my own research.

My question is this: is Cymbalta an SSRI as well, and if not (and even if so), am I putting myself in any immediate chemical danger from the drug interaction? Or should I still avoid tryptamines (especially psilocybin) and LSD even with an SNRI? I can't find any information on Cymbalta and recreational drug use contraindications. Ugh!

Your help is deeply appreciated. Peace!