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Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference.

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 #1 
Old 2008-02-13, 01:00
bobert the man bobert the man is offline
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Default Cross tolerance between Oxycodone and Morphine

Well, the two opiates i have begun to abuse have been oxy and codeine (which i guess is converted to morphine in the brain hence my title). Seeing as i know almost nothing about opes and brain chemistry, i was wondering, seeing as they both act on "opiate receptors", is there a cross tolerance between them? Ive been using oxy a decent bit, couple times a week, but i havent done codeine for a few weeks and i hope that it wont be affect.

And please no one tell me "theres no tolerance from a couple times a week" because i do know in fact i have a tolerance. Purely academic answers would be appreciated.
 #2 
Old 2008-02-13, 01:04
Internet-Weed-Dude Internet-Weed-Dude is offline
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Default Re: Cross tolerance between Oxycodone and Morphine

I have no idea. Why am I posting this then? that's fucked up.. good question though.
 #3 
Old 2008-02-13, 01:06
ingutted ingutted is offline
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Default Re: Cross tolerance between Oxycodone and Morphine

Quote:
Originally Posted by bobert the man
Well, the two opiates i have begun to abuse have been oxy and codeine (which i guess is converted to morphine in the brain hence my title). Seeing as i know almost nothing about opes and brain chemistry, i was wondering, seeing as they both act on "opiate receptors", is there a cross tolerance between them? Ive been using oxy a decent bit, couple times a week, but i havent done codeine for a few weeks and i hope that it wont be affect.

And please no one tell me "theres no tolerance from a couple times a week" because i do know in fact i have a tolerance. Purely academic answers would be appreciated.


well uh duh the'res a tolerance build up but not much i would assume.
 #4 
Old 2008-02-13, 01:11
Ave2 Ave2 is offline
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Default Re: Cross tolerance between Oxycodone and Morphine

(which i guess is converted to morphine in the brain hence my title)

the liver


Seeing as i know almost nothing about opes and brain chemistry

yes


i was wondering, seeing as they both act on "opiate receptors", is there a cross tolerance between them?

Duh.... http://www.thatspoppycock.com/opiates/images/oxycontin_conversion.jpg
 #5 
Old 2008-02-13, 07:26
Aces N 8S Aces N 8S is offline
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Default Re: Cross tolerance between Oxycodone and Morphine

there is a notable cross tolerance between all drugs that affect the mu-opioid receptors (all recreational opiates).
 #6 
Old 2008-02-13, 08:06
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Default Re: Cross tolerance between Oxycodone and Morphine

I'd assume that your tolerance for opes. is affected when you take any opiates and will be a factor when taking any other opiates...if that's what your asking. I'm not entirely sure as I am hypothetically really fucked up.
 #7 
Old 2008-02-13, 08:11
Ave2 Ave2 is offline
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Default Re: Cross tolerance between Oxycodone and Morphine

I am hypothetically really fucked up.

oxymoron

lulz
 
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