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| Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference. |
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#1
 2008-01-30, 01:58
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happyonehitter 
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Morphine plugging
So I got over the whole stigma thing, cos my oral tolerance was getting way too high (150mgs to get a nod), and that took about an hour and a half to reach peak effects.
Prepared 2 30mg MS tabs by crushing them into powder, dissolving into sterile saline (I doubt the purity of the water matters when plugging, but better to be safer), drawing up though an oral syringe, and up it went. Not too painful or anything, it was just weird cos stuff was going into my asshole, rather than exiting it. It only took a couple of seconds to get it all in, so I took out the syringe, wrapped it up securely for disposal, and lied on my stomach to let the solution absorb. 5 minutes later, I was nodding the fuck out, and the high lasted for about 4-5 hours.
Considering I went from 150mgs + 1.5hrs to nod, to 60mgs and just 5 mins before nodding (the next day as well, so a tolerance break was not a factor), I would definitely recommend plugging for those who want to maximise their morphine, but don't want to shoot. I also had qualms about plugging, but didn't want to waste any more like I previously was, so I thought 'fuck it', and by god was it strong. I almost even felt a rush, the kind of thing you'd imagine IV to be (obviously nowhere near as close).
Infinitely better than eating, snorting or parachuting. It's definitely my new ROA of choice for morphine, at least until I can get opes with a higher oral bioavailability.
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#2
 2008-01-30, 02:15
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Re: Morphine plugging
Theirs a better way to get more out of your morphine for non-bangers.
Take some chitosan along with 600mg's Tagamet, A cup of pure white grapefruit juice, and a cup of tonic, 45 minutes before snorting your morphine.
The bioavailability will be nearly twice that of plugging, and it'll last just as long if not longer, due to all the enzyme inhibitors (cimetidine, tonic, and grapefruit)
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#3
 2008-01-30, 02:31
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happyonehitter 
Regular
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Re: Morphine plugging
The bioavailability of plugging is around 60%, snorting is around 30%. Even if the chitosan and all the other stuff were to double (at least) the bioavailability, it is a lot easier to just prep for plugging-grind beads to powder, dissolve in warm water, draw up, and shove it up there. The onset and 'rush' are so much better with plugging than with snorting.
Although, I might follow the potentiation formula to the letter (I've done bits and pieces, e.g. tonic water once, baking soda another time, diph another) after I get all the 'ingredients', and try a potentiated plug. I reckon that would be awesome.
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#4
 2008-01-30, 02:41
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Re: Morphine plugging
Quote:
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Originally Posted by happyonehitter
The bioavailability of plugging is around 60%, snorting is around 30%. Even if the chitosan and all the other stuff were to double (at least) the bioavailability, it is a lot easier to just prep for plugging-grind beads to powder, dissolve in warm water, draw up, and shove it up there. The onset and 'rush' are so much better with plugging than with snorting.
Although, I might follow the potentiation formula to the letter (I've done bits and pieces, e.g. tonic water once, baking soda another time, diph another) after I get all the 'ingredients', and try a potentiated plug. I reckon that would be awesome.
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Actually oral and rectal administration have around the same bioavailability. But chitosan has been shown to increase nasal bioavailability of morphine from around 10-20% to over 60%.
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#5
 2008-01-30, 02:57
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happyonehitter 
Regular
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Re: Morphine plugging
Actually oral and rectal administration have around the same bioavailability. But chitosan has been shown to increase nasal bioavailability of morphine from around 10-20% to over 60%.
That's based on loads of different studies, which have found huge fucking variations in bioavailabilities for each ROA. Also, lots of people say that plugging is the next best thing to IV, which I also believe now.
I'm just describing how it was for me, in terms of dose/onset/etc...
ORAL (taken yesterday): 150mgs, 1.5hrs to nod
RECTAL (today): 60mgs, 5mins to nod
With both ROAs, the effects lasted for about 4-5 hours roughly.
Plus, even though I had a huge dose yesterday, I needed only 40% of that up my ass for the same effects, with a much faster onset, and the same duration of effects.
RECTAL > ORAL/INSUFFLATION
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#6
 2008-01-30, 03:17
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Internet-Weed-Dude 
Regular
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Re: Morphine plugging
Quote:
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Originally Posted by OMr_duckO
Theirs a better way to get more out of your morphine for non-bangers.
Take some chitosan along with 600mg's Tagamet, A cup of pure white grapefruit juice, and a cup of tonic, 45 minutes before snorting your morphine.
The bioavailability will be nearly twice that of plugging, and it'll last just as long if not longer, due to all the enzyme inhibitors (cimetidine, tonic, and grapefruit)
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Oh my god you are so fucking stupid it is unbelievable.
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#7
 2008-01-30, 03:24
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Re: Morphine plugging
Oh my god you are so fucking stupid it is unbelievable.
Trolls like you don't last very long. I just reported you, and I wouldn't be surprise if a fuckload of other people did too.
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#8
 2008-01-30, 04:04
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Aces N 8S 
Regular
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Re: Morphine plugging
Trolls like you don't last very long. I just reported you, and I wouldn't be surprise if a fuckload of other people did too.
you were wrong though.
you dont eat the chitosan 45 min before snorting, you snort then both in the same line.
(Source: L. Illum, et al, (2001) Intranasal delivery of morphine, The journal of pharmacology and experimental theraputics, 301, 391-400, 2002)
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#9
 2008-01-30, 04:09
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aTribeCalledSean 
Regular
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Re: Morphine plugging
Does plugging work with all opiates?
Aces N 8's holler, I'm on your campus!
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#10
 2008-01-30, 04:37
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Aces N 8S 
Regular
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Re: Morphine plugging
anything you can eat you can plug.
how long you on campus for homes?
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#11
 2008-01-30, 10:55
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aTribeCalledSean 
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Re: Morphine plugging
1. And it will always be stronger? (specifically hydrocodone)
2. Just powder, dissolve in water, and plug?
I'm just crashing at the GF's tonight. So I'll be here till I wake up tomorrow, probably around 11.
I wanna plug my Vic's bro, lol, help a brother out.
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#12
 2008-01-30, 13:45
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consciouscowboy 
Regular
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Re: Morphine plugging
Quote:
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Originally Posted by Aces N 8S
anything you can eat you can plug.
how long you on campus for homes?
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Even hotdogs???? 
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#13
 2008-01-30, 13:58
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eXo5 
Regular
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Re: Morphine plugging
for the record, it's holmes... and uhhh- plugging yeah > oral. period. salivatory glands in the anus are much larger than those in the nose. so plugging>insufflating.
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