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| Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference. |
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#1
 2008-01-18, 00:45
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J Christ 
Regular
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Intranasal Bioavailability or Psilocybin
I have scoured Google for this information and can't seem to find it. I know an oral dose is between 15-25mg @ ~50% bioavailability and I know how to calculate a dosage but I can't seem to find the information anywhere. Any help is greatly appreciated!
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#2
 2008-01-18, 00:59
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Pooter 
Regular
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Re: Intranasal Bioavailability or Psilocybin
Orally, cause it's going to burn like hell if you snort. Also, is it extracted of synthesized? extracted has EtOH.
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#3
 2008-01-18, 01:08
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Death Snuggle 
Regular
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Re: Intranasal Bioavailability or Psilocybin
Why is everyone so concerned with your sinuses burning after you snort something? Yeah, I've snorted my fair share of things and I know what it feels like, but it's not that bad. 2c-t-7 was the worst and it was only able to bring me to have a tear in one eye.
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#4
 2008-01-18, 01:44
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J Christ 
Regular
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Re: Intranasal Bioavailability or Psilocybin
Quote:
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Originally Posted by Pooter
Orally, cause it's going to burn like hell if you snort. Also, is it extracted of synthesized? extracted has EtOH.
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It is synthesized so it shouldn't have residual ethanol... I'm not worried about the burn, I'm curious as to experiment with the variation in duration and general level of intoxication, if you will, that would result from a different method of administration.
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#5
 2008-01-18, 01:46
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Re: Intranasal Bioavailability or Psilocybin
smoke that shit!!
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#6
 2008-01-18, 01:48
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Death Snuggle 
Regular
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Re: Intranasal Bioavailability or Psilocybin
It is synthesized so it shouldn't have residual ethanol... I'm not worried about the burn, I'm curious as to experiment with the variation in duration and general level of intoxication, if you will, that would result from a different method of administration.
Possible increase in the effects of the chemical, but also has the downside of being shorter. I hate taking RCs orally because it just doesn't do it for me, so I snort them. I'm using these as a rough example, mind you. I think it has potential to work, but I can't be positive.
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#7
 2008-01-18, 01:52
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ingutted 
Regular
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Re: Intranasal Bioavailability or Psilocybin
smoke that shit!!
you seem like a smart guy so im gonna assume sarcasm
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#8
 2008-01-18, 02:11
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J Christ 
Regular
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Re: Intranasal Bioavailability or Psilocybin
Possible increase in the effects of the chemical, but also has the downside of being shorter
I assumed this but I don't exactly want to blow 20mg and blow (pun very intended) my fucking mind. I have quite a bit so I'm not exactly worried about the duration as re-dosing will be very easy. I'm looking for a rough estimate but if I can't find one then I think if I start at 1/2 the oral dose and gradually bump extremely small amounts I can eventually find the correct dosage.
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#9
 2008-01-18, 04:31
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ingutted 
Regular
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Re: Intranasal Bioavailability or Psilocybin
I assumed this but I don't exactly want to blow 20mg and blow (pun very intended) my fucking mind. I have quite a bit so I'm not exactly worried about the duration as re-dosing will be very easy. I'm looking for a rough estimate but if I can't find one then I think if I start at 1/2 the oral dose and gradually bump extremely small amounts I can eventually find the correct dosage.
where do you get synth-ed psilocybin? just like an RC vendor?
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