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Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference.

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 #1 
Old 2008-01-17, 18:39
APguy APguy is offline
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Default DXM is a semisynthetic opioid?

http://www.youtube.com/watch?v=AvvsEj11mSU
 #2 
Old 2008-01-17, 18:43
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San Lorenzo
Default Re: DXM is a semisynthetic opioid?

That host needs a smack.
 #3 
Old 2008-01-17, 18:46
Death Snuggle Death Snuggle is offline
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Default Re: DXM is a semisynthetic opioid?

No, it just looks like one. It's molecular structure is mirror of one though.
 #4 
Old 2008-01-17, 18:53
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mah compound
Default Re: DXM is a semisynthetic opioid?

First it's people with chronic pain being denied meds in the name of the drug war, and next it's sick kids. Fuck you uncle sam, fuck you in your faggot ass.
 #5 
Old 2008-01-17, 18:59
Br00klynB0y87 Br00klynB0y87 is offline
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Default Re: DXM is a semisynthetic opioid?

DXM is actually fairly safe by itself.

What.. when used as directed, right?
 #6 
Old 2008-01-17, 19:01
Death Snuggle Death Snuggle is offline
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Default Re: DXM is a semisynthetic opioid?

God, this is just fucking annoying. I've looked at some of the other videos and any hope I had for humanity just died. They're idiots on both sides of this. Punch me in the face because I can't feel it... I fucking swear...

What.. when used as directed, right?

No, I'm mean don't a fucking idiot like the people I've met and down 1300mgs for your first time. You should be good with a fucking 3rd of that.
 #7 
Old 2008-01-17, 19:01
Br00klynB0y87 Br00klynB0y87 is offline
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Default Re: DXM is a semisynthetic opioid?

And btw those people look so dumb in that vid, talking about something which they haven't a fuxking clue... semisynthetic opioid.... :)lulz

.peace.
 #8 
Old 2008-01-17, 19:12
Br00klynB0y87 Br00klynB0y87 is offline
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Default Re: DXM is a semisynthetic opioid?

No, I'm mean don't a fucking idiot like the people I've met and down 1300mgs for your first time. You should be good with a fucking 3rd of that.

What?
 #9 
Old 2008-01-17, 19:17
Death Snuggle Death Snuggle is offline
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Default Re: DXM is a semisynthetic opioid?

What?

I meant it is a fairly safe drug to abuse. I've just had to deal with too many idiots thinking they can do more because they're hardcore and it pisses me off. He ended up almost killing himself. Stupidity just pisses me off.
 #10 
Old 2008-01-17, 19:17
Ave2 Ave2 is offline
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Default Re: DXM is a semisynthetic opioid?

check what your children are reading online...

there are evil websites that promote the use of cough medicine out there.
 #11 
Old 2008-01-17, 19:42
Br00klynB0y87 Br00klynB0y87 is offline
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Default Re: DXM is a semisynthetic opioid?

I meant it is a fairly safe drug to abuse.

I'm sorry but I'm going to have to disagree with you on that.

Now first, depending on the individual and their health status prior, they may be alright using it a couple times spread out over a period of time - that is also assuming the dosage is within a realistic measure for their body type.

But abusing DXM over a prolonged amount of time is definitely NOT safe in regards to your body as well as your mind...

Liver/kidney failure/toxicity ... bromism, brain damage/olsney's lesions (and no one knows for certain if olsney's lesions is likely, but still the fact that it has been theorized and very well may be possible should be more than enough of a reason NOT to abuse.

And yes I've fuxked with dex in the past, and in a way became psychologically addicted to it. After a couple months I realized wtf I was doing to both my body and mind- The simple task of formulating sentences to express oneself was a bit difficult... it just felt like I lost one to many brains cells and everything was slower to understand or remember...

Luckily that was suffered short term and after a period of time I was better and back to myself. But if I had abused it any longer I could have very easily suffered long term effects which would have not subsided.

.peace.
 #12 
Old 2008-01-17, 19:53
Death Snuggle Death Snuggle is offline
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Default Re: DXM is a semisynthetic opioid?

That's not how I meant it. I meant abuse in the sense that using anything over it's perscribed dose as abuse. I don't mean go chug it down 3+ times a week because it is very damaging to your sensory perception and your insides as well.

I've had my bout with DXM as well. I clung to the emotionless and painless creature I turned into everytime I was on it. I do wholely agree it completely fucks you over emotionly.
 #13 
Old 2008-01-17, 20:19
robinhoody robinhoody is offline
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Default Re: DXM is a semisynthetic opioid?

I haven't watched the video yet because Dropkick is more important, but I did want to touch on the synthetic opioid thing.

Depending on who you talk to, yes, DXM can be considered an opioid.

That was a point of contention here before, that lasted for a few months. https://www.totse.com/community/showpost.php?p=8134505&postcount=23
https://www.totse.com/community/showpost.php?p=8349927&postcount=16

For those that don't want to read the threads, synopsis: someone said DXM was an opioid, I said that it wasn't, because it showed no affinity for opioid receptors. Then they found a citation that claimed it showed very slight μ-OR affinity, but no one had access to the article. Fast forward a few months, I got in touch with the author, he explained that despite earlier assertions, DXM DOES show very minute μ-OR affinity. To visualize how minute, morphine's affinity is 0.3nM; DXM's affinity for the same receptors is 1,300nM (lower number = higher affinity).

So yeah, DXM can be considered an opioid, if you don't have limits on how low the affinity can be and still count. In which case, salvinorin is an opioid, too...
 #14 
Old 2008-01-18, 00:52
Br00klynB0y87 Br00klynB0y87 is offline
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Default Re: DXM is a semisynthetic opioid?

That's interesting.

Although still I think it's quite pointless to speak of it as an opioid when it has such a weak affinity for the μ opioid receptors.

.peace.
 #15 
Old 2008-01-18, 01:14
consciouscowboy consciouscowboy is offline
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Default Re: DXM is a semisynthetic opioid?

And yes I've fuxked with dex in the past, and in a way became psychologically addicted to it.

Stop calling it dex! :(
 #16 
Old 2008-01-18, 01:17
mari juana mari juana is offline
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Default Re: DXM is a semisynthetic opioid?

Stop calling it dex! :(

why not call it dex? dex is the shit.

dex dex dex dex
 #17 
Old 2008-01-18, 01:57
Death Snuggle Death Snuggle is offline
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Default Re: DXM is a semisynthetic opioid?

why not call it dex? dex is the shit.

dex dex dex dex

I think he get's it confused with dex amps. lol
 
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