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Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference.

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 #1 
Old 2008-01-13, 19:06
Death and His Grim Death and His Grim is offline
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Default Plugging Codeine?

Will this give it any boosted effect?
 #2 
Old 2008-01-13, 19:09
HippieFlipping HippieFlipping is offline
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Default Re: Plugging Codeine?

NO why the fuck are people willing to shove shit up there ass just to get a little bit higher if not any
 #3 
Old 2008-01-13, 19:35
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Mi.
Default Re: Plugging Codeine?

Your a retard.

Codeine sucks anyway.
 #4 
Old 2008-01-13, 19:54
I LIKE LOLS I LIKE LOLS is offline
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Default Re: Plugging Codeine?

Codeine is just a prodrug for morphine and a few other opioids. What limits your high most is your liver. It has 90% oral bioavailability, so plugging it would be a literal and metaphorical pain in the ass for just a small boost.
 #5 
Old 2008-01-13, 19:58
ilovechronic ilovechronic is offline
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Default Re: Plugging Codeine?

Doesn't it have to pass through the liver? I mean don't the enzymes in the liver hav to break down the codeine molecules into morphine? Thats how I thought it happend. Joe pedo, Let loose!
 #6 
Old 2008-01-14, 00:08
mahatmaganja420 mahatmaganja420 is offline
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Default Re: Plugging Codeine?

Yeah, you need it to pass through your liver in order for it to metabolize into Morphine. Not to mention the problems listed with IV codeine use, I'd be weary of plugging it. To all those homophobes out there, plugging isn't a big deal. If you don't want to, you don't have to. But you shouldn't be imposing your opinions on other people, especially when the only thing you have to back it up is "Ew that's gross". Grow up. While plugging can increase the "value" so to speak, of most drugs, it's not worthwhile for others. Like Oxycodone for instance has a high enough oral bioavailability, that plugging is sort of a waste of time. And yeah, Codeine does have a 90% oral bioavailability supposedly; it is still only ~10% the potency of Morphine. To be honest, I wouldn't waste my time trying. The risk to potential benefit ratio isn't looking so great. Just eat them, if you're worried about it not being enough here are a few suggestions. First of all, take all the Codeine as close to the same time as possible. I can't find the source, but I remember reading that Codeine inhibits enzymes that help metabolize it into Morphine. This means as soon as you take some, your body is going to have a harder time getting high off of more. (E.g. I once at 2 Tylenol 3s, but didn’t feel anything. So I ate 2 more, nothing, then another 2, still nothing, and ANOTHER 2; still felt nothing more than a dry mouth and a light buzz. The next day I took 4 all at once and was gloriously high.) Also, crush it into a powder and swallow it with Coca-Cola. I've found that it works VERY well for covering the god awful taste of APAP, not to mention the Caffeine in it (if you aren't used to drinking caffeine, which you may be) will increase the analgesic capabilities of the Codeine. Hope this was helpful. Also if this message is hard to follow in any way or whatever, it's because I'm in intense pain from what is probably a dry socket.
 #7 
Old 2008-01-16, 19:07
ilovechronic ilovechronic is offline
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Default Re: Plugging Codeine?

hey i said JOE PEDOE LET LOOSE. just kidding you help also.
 
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