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| Laboratory Tips Safety proceedures, test reagents, drilling rubber stoppers, bending glass tubes, etc. Contributed to by chemists. |
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# 1

2007-04-19, 12:35
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Regular
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oregon US
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purification of methamphetamine
what would i need to have and need to do if i wanted to, in theory of course, purify crystal methamphetamine?
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# 2

2007-04-19, 12:45
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Re: purification of methamphetamine
Separate it from impurities, in theory.
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# 3

2007-04-19, 13:22
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Regular
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oregon US
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Re: purification of methamphetamine
yea, any suggestions how? i would imagine that most of the cuts would be similarly soluble, but what kind of solvents would be best to use to separate out the impurities?
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# 4

2007-04-19, 13:26
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Regular
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Ol Blighty
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Re: purification of methamphetamine
Swiy could use chloroform which will draw up the MA but leave behind any unreduced ephedrine (pse too, I think). However, for a simple and quick clean use some ice cold, dry acetone (dry is preferable but one could get away with using it straight as it is , usually without much loss). Drying is easy - just add oven dried epsom salts to the acetone (dry the epsom by putting them in the oven for an hour or so or you could microwave them for 10 or 20 mins) give it a god shake around and leave for an hour or so just to make sure every last bit is absorbed and filter out the epsom salts and you have dry acetone. Put your MA in a coffee filter and pour the acetone over the MA (you will get best results if the MA is ground to a powder to ensure every bit of it is purified).
A dual solvent recrystalisation in acetone and alcohol is also good or even the MEK boil - plent y of info available on both.
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# 5

2007-04-19, 13:50
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Regular
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AL
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Re: purification of methamphetamine
Quote:
Originally Posted by UK_TOM
A dual solvent recrystalisation in acetone and alcohol is also good or even the MEK boil - plent y of info available on both.
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DITTO! Dual solvent with 91% ISO. The other part of the dual is the 9% H2O in the iso.
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# 6

2007-04-19, 15:28
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Re: purification of methamphetamine
Quote:
Originally Posted by speedfreak420
yea, any suggestions how? i would imagine that most of the cuts would be similarly soluble, but what kind of solvents would be best to use to separate out the impurities?
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Well, for future reference, you should be interested in what dilutants are out there, such as MSM, and work from there. You may be able to chemically separate, dissolve, distill, or even physically sieve out impurities within substances based on the physical (and even chemical for the more advanced) properties differing between the two.
It's just tedious research you have to do yourself.
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# 7

2007-04-19, 18:16
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Regular
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oregon US
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Re: purification of methamphetamine
ok. how about diethyl ether as a solvent? or would the impurities most likely be soluble in that? because thats all that i have just sitting around, no acetone, no MEK, not much else that i can think of that would do me any use
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# 8

2007-04-19, 18:50
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Re: purification of methamphetamine
Gosh, if I knew what impurities you meant, I might have an easier time with that. Dilutants? Byproducts? If byproducts, what method did you use to manufacture said meth? You do understand that a different chemical equation will yield different byproducts, right? Not to be a jerk, but you see what I go through when I read a vague post? I have no idea where to begin, and very little drive to respond at all.
I'd guess that a good deal of impurities would dissolve, seeing as how that's a real good non-polar solvent.
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# 9

2007-04-19, 19:39
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Re: purification of methamphetamine
You need need impure meth, and 2 pieces of glassware (beaker prefered large enough to hold it in a a heat source. You would also need a solvent (either one that's not flamable or use a non-sparking heat shorce such as a steam bath or high quality labrotory hot plate. Lets just say acetone for starters. heat the solvent to near boiling, add slowly until all the solid has just been barely disolved, Then allow to stand cool to room temp, crytals should form, but mabye they wont. Stratch ten inside of the beaker or add a seed crystal, than cool in an 1:3 V:V salt to ice bath (shoub be about -25 degC. then filter out the crytals. If you didn't yeild as much as you had hoped, boild off some tone until the solution become cloudy, add a couple drops of tone until the solution clears, then cool it again and filter out the crystals
This won't work that well it it's bee severely cut, less than 70% pure. Also keep the bathes seperate, the second yeild of crystals will be less pure than the first.
If you're really paranoid, react it in a two phase (water/DCM) to to form it's chloride salt, sepearte the phases and basify the aqueous phase,(to ph 9 should be sufficient) then cool on an ice-water bath and crystals should fall out of the aqueous solution. Collect by filtration.
The ultimate purification techniques would be vacuum distillation
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# 10

2007-04-20, 02:07
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Re: purification of methamphetamine
I heard a rumor, that I've never cared if it was correct, not being a tweaker, that the shit actually responds to blacklight.
Hmm. At that point, I'd probably shout "zomg this is too fucking easy" and chromatograph under blacklight, before recrystallizing the selected fraction in aqueous acetone. I'd guess, just out of my ass, that the ma huang byproduct of the n,n-dimethyl analog would *probably* move slightly more slowly in aqueous solution, but... pfft. What do I know, eh?
In fact... I'd probably recrystalize from aqueous acetone in a deeeep freakin' water bath over the course of several days with a watchglass, just to get the kind of giant organic crystal that you could run around town stabbing people to death with... because there's something beautifully poetic about a 1oz flawless crystal.
I guarantee you, a 1oz shard of any coveted organic molecule will get you pussy.  It's just that cool.
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This thread continued for 2 pages in the real archive, 18 posts total - only page 1 survived here.
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