Been noticing a slow phasing out of the pseudo, and the integration of Loratadine on the shelves.

Has anyone tried to do anything woth that? Seems to have the same general effect (judging by the packages, and usages)

Also looks more potent. 10mg Loratadine does the same thing as 30 to 60mg pseudo HCI.

If it's more potent, and can be used, why hasn't anyone else tried it yet?

If I had more of a chemistry knowledge, and IF I knew more about it, I would know, but as I don't, here I am, asking the pros!!

quote:Been noticing a slow phasing out of the pseudo, and the integration of Loratadine on the shelves.You're probably noticing thisfrom its being added/included to the limited shelf space of the decongestant aisle. Pseudo isn't going anywhere fortunately enough.



[/QUOTE]Has anyone tried to do anything woth that? Seems to have the same general effect (judging by the packages, and usages)[/QUOTE]It's the generic name for the now expired patent of Claritin. Which is an anti-histimine. Really it got such fan-fare as it did because its an anti-hist that doesn't cause drowsiness like Benedryl or Tripolidine etc.

[/QUOTE]You sure?! The generic claritin is packaged with pseudoephedrine sulphate anyway isn't it?!Don't quote me here but I think that's the case. It's pharmacolgical action is polar-opposite that of pseudo though.

quote:If it's more potent, and can be used, why hasn't anyone else tried it yet?

If I had more of a chemistry knowledge, and IF I knew more about it, I would know, but as I don't, here I am, asking the pros!!Well said. Simple enough.

I'll post below me here the PDR-entry to these two active ingredients.

Jam. <A HREF="http://users.pandora.be/eforum/emoticons4u/smoking/rauch11.gif">http://users.pandora.be/eforum/emoticons4u/smoking/rauch11.gif" width="90" height="90 (http://users.pandora.be/eforum/emoticons4u/smoking/rauch11.gif" width="90" height="90)</A>

DESCRIPTION

Loratadine is a long-acting antihistamine having the empirical formula C22H23ClN2O2; the chemical name ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate.

The molecular weight of loratadine is 382.89. It is a white to off-white powder, not soluble in water,but very soluble in acetone, alcohol, and chloroform. <A HREF="http://users.pandora.be/eforum/emoticons4u/fingers/fing32.gif">http://users.pandora.be/eforum/emoticons4u/fingers/fing32.gif" width="90" height="90 (http://users.pandora.be/eforum/emoticons4u/fingers/fing32.gif" width="90" height="90)</A>

Pseudoephedrine sulfate is the synthetic salt of one of the naturally occurring dextrorotatory diastereomers of ephedrine and is classified as an indirect sympathomimetic amine. The empirical formula for pseudoephedrine sulfate is (C10H15NO)2*H2SO4; the chemical name is a-[1-(methyl-amino) ethyl]-[S-(R*,R*)]-benzenemethanol sulfate (2:1)(salt).

The molecular weight of pseudoephedrine sulfate is 428.54. It is a white powder, freely soluble in water and methanol and sparingly soluble in chloroform.

Claritin-D 12 Hour Extended Release Tablets

Claritin-D 12 hour extended release tablets contain 5 mg loratadine in the tablet coating for immediate release and 120 mg pseudoephedrine sulfate equally distributed between the tablet coating for immediate release and the barrier-coated extended release core.

The inactive ingredients are acacia, butylparaben, calcium sulfate, carnauba wax, corn starch, lactose, magnesium stearate, microcrystalline cellulose, neutral soap, oleic acid, povidone, rosin, sugar, talc, titanium dioxide, white wax, and zein.

Claritin-D 24 Hour Extended Release Tablets

Claritin-D 24 hour extended release tablets contain 10 mg loratadine in the tablet film coating for immediate release and 240 mg pseudoephedrine sulfate in the tablet core which is released slowly allowing for once-daily administration.

The inactive ingredients for oval, biconvex Claritin-D 24 hour extended release tablets are calcium phosphate, carnauba wax, ethylcellulose, hydroxypropyl methylcellulose, magnesium stearate, polyethylene glycol, povidone, silicon dioxide, sugar, titanium dioxide, and white wax.

Didn't take chemistry in schol, lol. I guess what I was wondering, was...

Can loratadine be used if the pseudo goes away? Seems to be everywhere.

I dunno, maybe I'm just thinking too far ahead, and in the wrong direction, lol

Time for this old man to finish watching Bowling for Columbine, and toddle off to bed.

Happy new year everyone!