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| Laboratory Tips Safety proceedures, test reagents, drilling rubber stoppers, bending glass tubes, etc. Contributed to by chemists. |
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#1
 2003-11-14, 04:28
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Sphinx 
Regular
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Extracting Ephedrine from Tablets??
I have tablets that are 25mg ephedrine per tablet.
Thats all they are, is ephedrine. Now I assume I cant just crush them up and it'd be powder ephedrine, I assume I have to break down and remove the binding agent used to keep the tablets together... correct?
I dont know what binding agents been used in them... is that a problem?
How do I remove the binding agents so thats all thats left is the ephedrine... or could I just crush the tabs up and use them for whatever I seek?
THIS IS NOT SUDDAFED, these are PURE ephedrine tablets, no other ingredients other than the binding agent.. (if a binding agents even used).
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#2
 2003-11-14, 04:42
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sam-63 
Regular
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Re: Extracting Ephedrine from Tablets??
Yes I would be almost cveratin that they contain a binder, but for the most part those seem to be some nice polutant free tablets, look in the inactive ingredients that will tell you what has been used in the binding. But here is the method I use to do this job, there are other ways as well, please do yourself a favor though next time, do a little research here and you will find that your question has been aswered repeatedly.
Acidmelts
Easy Extraction of Psuedo
This is the most basic simple way of extracting psuedoephedrine from OTC cold medicine. I know that in other Countries (Oz) they add a bunch of stupid shit to pills to make it hard to do extractions, but this is for places that don't do that. Here in America it is easy to accuire good pills that are easily extractable.
Here is how it works...
Purchase as many pills as you feel necessary for your reaction. In my dreams I usually get about 300 to 400 white pills containing 60mg of psuedoephedrine Hcl. Get the cheapest, most generic pills. (Hint... try dollar stores) Remember that if you get pills with red dye on them you have to get the dye off first. That is covered in another page on Chemhead.
Now put all the pills in a ziplock baggie and close it up good. Crush up the pills with a hammer. Now pour the powdered pills into a glass jar and cover with twice as much methanol. (the gas line antifreeze Heet containes methanol) If you have 2 inches of powder in your glass jar then cover with about 4 inches of methanol. Shake up really good.
Now put this jar into your fridge and let it sit for about 3 hours. Then take out of the fridge and siphon all the methanol through some plastic tubing. (aquarium tubing) Siphon this into a funnel with 2 coffee filters and a cotton ball in the end. The funnel should be sitting on top of another glass jar. Now set this aside for the moment.
Take your first jar with gunky pill shit in the bottom, and add a little more methanol to it. (about 2 inches worth) Now shake it up again real good, and set it back in the fridge for about 2 hours or until it the methanol starts to look sorta clear again. After the gunk all settles to the bottom again take out of the fridge and siphon the methanol back through the same funnel with the same filters and into the glass jar with the methanol in it from the first siphon.
Take all your methanol and put it a glass visionware bowl and put it on your ELECTRIC burner or stove. It has to be electric, if you use gas chances are you will blow yourself up. Now put it on medium heat and slowly boil down your methanol until it is almost all gone. Now take off the stove and finish drying with a hairdryer. Make sure it is totally dry.
Now add a small amount of d-H2O(distilled water) to the bowl with the powder in the bottom and stir with a plastic spoon until it looks all dissolved in the water. Now set this in the freezer for about 45 minutes. While this is chillin, set up another funnel with 3 coffee filters and a cotton ball or 2 in the tip. put this over a new glass jar. Be sure to pre-wet the filters with d-H2O. Now take the bowl out of the freezer and pour the contents of the visionware bowl through the filters. It will probaly take a while since the water/psuedo will be kinda frozen from being in the freezer. This freezing process will get all of the waxes and binders out of your solution. You will notice after filtering that there is a nice thick layer of binders covering your filter. After it all filters through, take out the top of the 3 filters and discard. Add a new one in its place. Now keep running your water/psuedo through you filter until the water looks perfectly clear. This usually take me about 4 or 5 times in my dreams.
Now you have to dissolve the d-H2O like you dissolved the methanol. Put it in your clean visionware bowl and set on the burner on medium heat (a soft boil). Don't go anywhere! Stand there and watch it. When it gets down real low again take off the burner and finish with a hairdryer. You do this cause it burns real easily. Now you have pure (or close to it) psuedoephedrine Hcl crystalized in the bottom of yor bowl.
All right your almost done. This final cleaning REALLY helps out your psuedo. what you are going to do is cover your psuedo with an anhydrous non-polar solvent (Toluene, Colemans Fuel, ect.).To make your NP anhydrous you will need to pour it over some cooked epsom salts (put on a cookie sheet in the oven at 300F for 2 hours). What this does is suck the water out of your NP making it anhydrous. Make sure you cover your psudeo well but dont put in too much. Now stir it up a little. The non-polar solvent wont dissolve you psuedo but will clean more crap off of it. Now put your visionware bowl ( with the psuedo and NP in it) onto your electric burner. Keep it on very low heat. Watch carefully.... when it starts to boil take off the heat and stir a bit till it calms down, and put it back on. you want to boil for 5 minutes. now just pour it all through a filter. This will catch all your psuedo. Discard the dirty NP. Now repeat the process 2 more times so that you have a total of 3 boils in your anhydrous NP solvent. Now just put your psuedo in a clean jar and pour in some anhydrous acetone (same as before... pour through cooked epsom salts). Stir very well and pour though a filter one more time. Discard the Acetone. Now in your filter you have some fuckin SUPER pure psuedo. Have fun with it!
[This message has been edited by sam-63 (edited 11-14-2003).]
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#3
 2003-11-14, 05:39
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Wicked_Rain 
Regular
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Re: Extracting Ephedrine from Tablets??
the pills sphinx refers to and the pills you are talking about sam are as different as buffalos and grasshoppers. most likley the pills he refers to are a dietary aid or something of the kind. in which case there may not be an inactives list. you can bet there are other things in them tho as .25 mg of ephedrine would be a pill smaller than a pinhead. not to mention the extraction method you posted is outdated and will not be clean at all. time to do some research and catch up with some new techniques that have been offered. but hey what do i know.
[This message has been edited by Wicked_Rain (edited 11-14-2003).]
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#4
 2003-11-14, 06:08
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Sphinx 
Regular
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Re: Extracting Ephedrine from Tablets??
The tablets are not .25mg, they are 25mg
They are for bodybuilders basically (ephedrine is a great fat cutter -- as i bodybuild personally and love it). Theyre just pure ephedrine as far as I am aware.
This is not a ECA stack, this is just pure ephedrine pills.
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#5
 2003-11-14, 06:09
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Sphinx 
Regular
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Re: Extracting Ephedrine from Tablets??
I assume ill need a different method?
Shouldnt Methanol be sufficient for dissolving any binding agents?
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#6
 2003-11-14, 07:07
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kirby 
Regular
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Re: Extracting Ephedrine from Tablets??
i think i know the pills you have..
do they come in a little dark glass bottle with cotton wool in the end
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#7
 2003-11-14, 08:32
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Spook 
Regular
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Re: Extracting Ephedrine from Tablets??
yeah 25mg is still a very small pill.. they will have fillers and binders in there too.. methanol may dissolve the binders and be appropriate if ephedrine is in freebase form ..i don't know enough about binders to comment.. couldn't he try a MeOH wash with a few pills and see what he gets ?? if it doesn't work he can just evap and all will still be there??
surely they would not be that clean ??
[This message has been edited by Spook (edited 11-14-2003).]
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#8
 2003-11-14, 10:18
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kirby 
Regular
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Re: Extracting Ephedrine from Tablets??
ok
ive dealt with those pills
down here sigma aldrich puts them out
little white pill
about 0 big..
grind pills up to fine powder..
2 dry freezing acetone washes,fine filtering each time..
3 extractions with isopropyl alcohol if you can get it..
methanol can be used if you have to..
evap off all alcohol till first scale appears..
into freezer for 3 hours..
drain off the liquid from the pin needles and save needles for reduction..
dry liquid and clean with acetone...
dissolve left over powder after acetone wash into alcohol...
evap alcohol til scale appears
freezer for 3 hours
keep repeating till no more pins appear
good luck
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#9
 2003-11-14, 18:49
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Sphinx 
Regular
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Re: Extracting Ephedrine from Tablets??
Thanks bro.
Ill keep that idea in the back of my mind. However something else has come up, I want yours (or anyones) opinion on this... heres the quote
"bulk ephedra extract powder 8% if you are interested, but not pharmaceutical. If you want big amounts of ephedrine HCL by the KG..."
Now im no wizard with this, but wuts the 8% mean? Does that mean the powder is 8% ephedrine? I dont fully understand...
For the ephedrine used in the METHod's, is it HCL or what? Sorry I know this has probably been asked before, but I like to ask my questions personally.
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#10
 2003-11-14, 19:38
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madchemist 
Regular
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Re: Extracting Ephedrine from Tablets??
Are you sure they are ephedrine and not EHPEDRA? Ephedra is extract of the plant, which contains more than ephedrine. If you live in US then it is certainly ephedra (as ephedrine is banned), and SWIM doesn't suggest to use them. If not, or they are from an old bottle laying around or something, then go for it.
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#11
 2003-11-14, 21:59
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Wicked_Rain 
Regular
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Re: Extracting Ephedrine from Tablets??
quote:Originally posted by Sphinx:
I know this has probably been asked before, but I like to ask my questions personally.
TRANSLATION:
(1)im to lazy to do my own research.
(2) i dont fully understand what is going on and cant understand how to gleen the needed info from reading thru other past threads.
(3) im a cop and i want to see who knows what and who might incriminate themselves.
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#12
 2003-11-17, 06:22
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Sphinx 
Regular
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Re: Extracting Ephedrine from Tablets??
Okay, the 25mg pills have no fillers at all. Its 25mg's ephedrine, not ephedra.
So should I stick to kirby's idea?
Alls thats in them is some kind of binder, not sure what.
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#13
 2003-11-17, 06:31
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kirby 
Regular
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Re: Extracting Ephedrine from Tablets??
ok
the binder is like a wall plaster,,plaster of paris we call it,,same stuff they use to make plaster casts for broken limbs..
and yes,,stick to the method that petty fool kirby wrote in his previous post
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#14
 2003-11-17, 06:33
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Sphinx 
Regular
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Re: Extracting Ephedrine from Tablets??
Oh and Wicked...
a) I am too busy researching neuroendocrinology and osteophysiology
b) I dont have the extra time
c) YOUR GOING TO JAIL
LOL get real you paranoid pothead, lay off the chronic.
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#15
 2003-11-17, 06:36
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kirby 
Regular
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Re: Extracting Ephedrine from Tablets??
with ephedra
id presume the 8% means the eph content is 8%of the bulk weight
which is very high
usually 2% to 3% is a good percentage
8%has got to be the best china herb they have
id grab it
takes all day to get the alkaloid out of 100kgs
takes another day to turn it from an alkaloid to a salt
but then you have enough eph to stun a gym
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#16
 2003-11-17, 06:42
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Sphinx 
Regular
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Re: Extracting Ephedrine from Tablets??
Oh btw, I can get 10% ephedra, not 8%.
But ima go with the pills, since id much rather get 25mg ephedrine HCL rather than the extract bullshit.
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#17
 2003-11-17, 08:16
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kirby 
Regular
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Re: Extracting Ephedrine from Tablets??
and id bet someone is yanking your chain,,
10%ephedra is to good to be true
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#18
 2003-11-17, 09:56
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Wicked_Rain 
Regular
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Re: Extracting Ephedrine from Tablets??
quote:Originally posted by Sphinx:
Oh and Wicked...
a) I am too busy researching neuroendocrinology and osteophysiology
b) I dont have the extra time
c) YOUR GOING TO JAIL
LOL get real you paranoid pothead, lay off the chronic.
LOL ..im much better nowwww
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#19
 2003-11-17, 10:12
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kirby 
Regular
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Re: Extracting Ephedrine from Tablets??
i dunno sphinx,
pretty suspicious,
i dont think your a cop,
just another one who is is addicted to himself,,
self involved is the term
usually children to young adults suffer it,,
most lose it in there very early 20s,,
do you find that fellow in the mirror to be smart and good looking
do you answer your own questions often
do you like being the centre of attention,
do you sulk when you dont get your own way,
do you find that you have no long term friends,
do you feel that sex with yourself is far better than with anyone else
now that yourve answered yes to all those,,
you can put your hand back in your pants
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#20
 2003-11-17, 21:24
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madchemist 
Regular
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Re: Extracting Ephedrine from Tablets??
quote:
LOL get real you paranoid pothead, lay off the chronic.
I think the better answer for people like us is "GET SOME SLEEP". Everyones a cop by the fifth or sixth day.
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#21
 2003-11-17, 23:26
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Wicked_Rain 
Regular
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Re: Extracting Ephedrine from Tablets??
yep one time i stayed up so long i thought i was a cop. by the time the psychosis wore off there wasnt a donut within 200 miles.
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#22
 2003-11-18, 05:38
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sam-63 
Regular
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Re: Extracting Ephedrine from Tablets??
swim has dealt with those exact tabletsd sdeveral times, ordered from the great white north, Heet cleaned them up nicely, swim wished that the customs wouldn't have cracked on them, they were some great soup starters.
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