ok im no chemist, but i have been reading lots on organic chemitry, and theres been a question that has been in my mind for some time,

although it probloly will sound ridiculase to you, you have to consider my lack of knowlage on this subject.

ok here goes.

could someone make new drugs or what would happen if you reacted two drugs together?

for instance, if u reacted dextromethorphan with MDMA, or THC and fentanyl.

thanks for your time. X Hixxy X.

They may not react to begin with, and even if they do, you probably wouldn't get any useful chem's from it. Or insofar as i know.

Dude! If you mixed all four of those in a flask added dihydrogen monoxide while gently heating.

You'd yield a new super drug!

Most drugs aren't very reactive, it takes a fairly active reagent to affect a change in an organic molecule. So just mixing two quite unreactive chemicals is not going to result in anything interesting happening.

On the other hand if you meant combining them using another reagent to condense them there are possibilities(of uninteresting things happening, but still there)

If you have a reactive site or you make one on a given drug, say you take oxycodone which has a ketone functional group on it instead of DXM, and you react it with amphetamine in a mildly acid environment, you will get a sort of frankendrug with the two components tied together through an imine bond.

Unfortunately this messes up the three dimensional structure of both drugs, and this is bad. The 3-d structure of a drug determines it's SAR (Structure Activity Relationship) fitness for a receptor in your noggin. The 3-d position of certain charged and non-polar groups on the molecule are what gives them their activity. We have learned that slightly modifying some groups(change a methoxy to an ethoxy, OH to SH) tweaks the activity more to our liking. However going too far, blocking certain sites or adding too much to your basic active drug will ruin its fit for a particular receptor.

Simply put: hanging a dead wombat off the side of any drug is going to make it useless.

yeah right tryp,,we all understood every word of that mate