Anyone know exactly how soluble methcathinone is in acetone and would it work well in crystallization?

Ask and ye shall recieve....



6033. Methcathinone.

2-(Methylamino)-1-phenyl-1-propanone; .alpha.-methylaminopropiophenone; monomethylpropion; ephedrone; Jeff; mulka; cat; cosmos; Jee cocktail. C10H13NO; mol wt

163.22. C 73.59%, H 8.03%, N 8.58%, O 9.80%. Oxidation product of ephedrine possessing amphetamine-like central stimulant properties. Prepn: J. F. Hyde et

al., J. Am. Chem. Soc. 50, 2287 (1928); K. Y. Zhingel et al., J. Forensic Sci. 36, 915 (1991). Prepn of enantiomers and chromatographic analysis: J. DeRuiter et al., J.

Chromatog. Sci. 32, 552 (1994). Comparative pharmacology: R. Young, R. A. Glennon, Pharmacol. Biochem. Behav. 45, 229 (1993). Pharmacology of enantiomers:

R. A. Glennon et al., ibid. 50, 601 (1995). Absorption and metabolism: S. L. Markantonis et al., J. Pharm. Pharmacol. 38, 515 (1986). GLC/MS determn in

urine: eidem, Chim. Chron. 14, 211 (1985). Impact on public health: T. S. Emerson, J. E. Cisek, Ann. Emerg. Med. 22, 1897 (1993).

Note: This is a controlled substance (stimulant) listed in the U.S. Code of Federal Regulations, Title 21 Part 1308.11 (1995).

Hydrochloride, C10H13NO.HCl,crystals from alcohol-acetone, mp 176-177 deg.

l-Form hydrochloride, C10H13NO.HCl. Prepn: Y. J. L'Italien, M. C. Rebstock, U.S. pat. 2,802,865 (1957 to Parke, Davis). Crystals from ethanol-ether or

chloroform-petr ether, mp 182-183 deg. Pungent taste. [.alpha.]D25 -53 deg (c = 1 in water). Sol in water. LD50 in mice, rats (mg/kg): 106, 90 iv; 233, 86 sc; 342, 99 orally

(Emerson).

Hmmm... Very interesting, I've been looking all over for this. Thanks, I appreciate the info.