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| Laboratory Tips Safety proceedures, test reagents, drilling rubber stoppers, bending glass tubes, etc. Contributed to by chemists. |
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#1
 2003-08-08, 05:28
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J. A. Seed 
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Loperamide (immodium)--->Demerol
Any gifted chemists wanna venture into this one
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#2
 2003-08-29, 07:32
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em de em aye 
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Re: Loperamide (immodium)--->Demerol
I was wondering if their was an easy way to use immodium to make some sort of recreational opiate.
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#3
 2003-08-29, 08:07
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suttleila 
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Re: Loperamide (immodium)--->Demerol
wtf lol heroin is not a stimulant its a downer don't noone here like being down....we like beingggggggg up real up =)
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#4
 2003-08-29, 09:56
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Wicked_Rain 
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Re: Loperamide (immodium)--->Demerol
quote:Originally posted by suttleila:
wtf lol heroin is not a stimulant its a downer don't noone here like being down....we like beingggggggg up real up =)
there it is!!!
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#5
 2003-08-29, 18:35
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J. A. Seed 
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Re: Loperamide (immodium)--->Demerol
quote:Originally posted by suttleila:
wtf lol heroin is not a stimulant its a downer don't noone here like being down....we like beingggggggg up real up =)
you gomer
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#6
 2003-08-30, 00:18
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J. A. Seed 
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Re: Loperamide (immodium)--->Demerol
Immodium is an opiate. It just doesnt cross the blood brain barrier. I wonder if theres any potentiator you could take to make it active. (ie DMT+MAOI) If thats impossible it shouldnt be too hard to change the molecule into an active opiate. This is all well above my head so if anyone has anything intelligent to add I would appreciate it
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#7
 2003-08-30, 01:16
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Follylover 
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Re: Loperamide (immodium)--->Demerol
It seems, as DXM is the triple de-meth ed right handed verson of that one, it is more than possible to change either into some kinda something fun. I will look into it, and find references.
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#8
 2003-08-30, 01:54
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Follylover 
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Re: Loperamide (immodium)--->Demerol
Abuse potential of loperamide
by
Jaffe JH, Kanzler M, Green J
Clin Pharmacol Ther 1980 Dec; 28(6):812-9
ABSTRACT
Effects of the currently marketed form of loperamide (Imodium capsules) that might relate to abuse potential were examined. Study I was a double-blind "dose run-up" in adult male subjects with a history of illicit drug use but no history of opioid addiction. Subjective responses to doses of loperamide ranging from 12 to 60 mg were compared with responses to 120 mg codeine sulfate (96 mg base) and to placebo. Based on study I, loperamide (60 mg) was used in study II and its effects were compared with those of codeine (96 mg base) and placebo in an exaddict subject group. Study II subjects had had extensive opioid experience but were not actively addicted at the time of this double-blind, inpatient study. In study II, as in study I, unlike loperamide and placebo, codeine induced pupillary constriction. Loperamide (60 mg) induced a detectable subjective effect in somewhat over half the subjects, was "liked" little or not at all, and was identified as "dope" at a frequency less than that for a threshold dose of oral codeine. It was concluded that in its present form, i.e., capsules containing loperamide mixed with magnesium stearate, loperamide poses little threat of potential abuse.
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#9
 2003-08-30, 04:21
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J. A. Seed 
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Re: Loperamide (immodium)--->Demerol
that would suggest that in some form it is indeed abusable for a starter how would you remove magnesium stearate from the loperamide
[This message has been edited by J. A. Seed (edited 08-30-2003).]
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#10
 2003-08-30, 05:58
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0.S. Sparkel 
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Re: Loperamide (immodium)--->Demerol
has anybody ever seen Heroine Shards? I was thinking about buying some Oxycontin 80's and trying to isolate the Oxycodone HCl, then somehow get it to form a crystal that would vaporize in a glass pipe or chase it on some Rynolds (HD). What about one big THC shard? Every substance forms a crystal under the right circumstances. Shit, this whole fucken planet is made of nothing but crystals!
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#11
 2003-08-30, 09:46
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J. A. Seed 
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Re: Loperamide (immodium)--->Demerol
quote:Originally posted by Follylover:
It seems, as DXM is the triple de-meth ed right handed verson of that one, it is more than possible to change either into some kinda something fun. I will look into it, and find references.
YES junkies of the world unite!!!!!!!!!!
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#12
 2003-08-30, 11:38
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suttleila 
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Re: Loperamide (immodium)--->Demerol
lol os man eveyrone substance don't turn into a crystal and dude i want some of what your own haha =) swim thought he had the fireee i think swirl has him beat cause you know a fool is geeking when he starts seeing everything as a crystal lol thc and all those other things cannot be turned into a crystal lol it can however be smoked on the foil =) enjoy the coughing i got one for u try this lol take some weed drop it in acetone shake the shit out of it then slowly drop in hcl then shake the shit out of it then evaportate then drop in acetone again lol then filter off for nice crystals how yall like that post =) itz called hash and is pure thc which is not crystals goodluck makin them tho and if ya do we all wanna know how im sure even tryp would like to know that...................damnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnn i need some of the shit yall are on 4real and i need sleep lol haven't been to sleep in 5 dayz and damn im starting to see shit =)
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#13
 2003-08-30, 17:00
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0.S. Sparkel 
Regular
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Re: Loperamide (immodium)--->Demerol
No actually, if you were to issolate any substance so that it is pure. Then heat it to melting point, cool it down very slowly, a centerfuge crystal will form in the middle, and the whole mass will eventually form into 1 big shard. This is true for any pure substance on earth.
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#14
 2003-08-30, 17:23
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Wicked_Rain 
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Re: Loperamide (immodium)--->Demerol
quote:Originally posted by suttleila:
lol os man eveyrone substance don't turn into a crystal and dude i want some of what your own haha =) swim thought he had the fireee i think swirl has him beat cause you know a fool is geeking when he starts seeing everything as a crystal lol thc and all those other things cannot be turned into a crystal lol it can however be smoked on the foil =) enjoy the coughing i got one for u try this lol take some weed drop it in acetone shake the shit out of it then slowly drop in hcl then shake the shit out of it then evaportate then drop in acetone again lol then filter off for nice crystals how yall like that post =) itz called hash and is pure thc which is not crystals goodluck makin them tho and if ya do we all wanna know how im sure even tryp would like to know that...................damnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnn i need some of the shit yall are on 4real and i need sleep lol haven't been to sleep in 5 dayz and damn im starting to see shit =)
pure hash is by no means done thru any chemical process. the crystals you see on good strains of weed where the buds look like they been rolled in sugar. these are what are harvested to obtain pure hash. SWIM was in morrocco once and watched as hash was being harvested. the women of the village went to the weed fields and worked all day long running there hands up and down the buds. several times thruout the day they rubbed there hands together in a circular motion producing BIG hash balls that were then dropped into a basket and the process started all over again. the name of these that we call crystals in laymens terms are actually called trichomes. look at them thru a 30 power pocket microscope and you will see they are indeed a crystaline structure. real hash has never had a chemical near it. hash produced from chem proceses is known as isomized hash. after SWIM seen what he seen in morrocco he quit using scissors to trim his crops and started using just his hands plucking the leaves and such ALL by hand. SWIM and his buddy once did 160 3 foot tall plants and gathered 177 grams of PURE hash. SWIM had it on the pads of his finger tips 1/4 inch thick and it rolled back over the fingernails halfway covering the fingernail. peeled it off and continued harvesting and peeling untill we were done. it was left out to dry and then put into an altoids mint can. a week later SWIM was smoking some with some friends at work and as SWIM was loading his pipe he noticed that one of the fingertip shaped dried hash pieces had a perfect impression of a fingerprint on it. SWIM then looked at the other chunks and yep every piece that was still whole had a perfectly clear fingerprint on the side that was peeled from the finger. SWIM laughed when he realized the evidence that was so clear if SWIM woulda got pulled over and had his tin of hash found. after that SWIM made sure to smash the round pads of hash so the prints were no longer legible. lol just a tidbit i thought id share.
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#15
 2003-08-30, 17:47
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0.S. Sparkel 
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Re: Loperamide (immodium)--->Demerol
yeah finger hash is badass. I fucken can make a 7+ grams just from triming (w/ scissors) like in 6 hours (bomb Humboldt outdoor)!
My favorite type of hash is issolated by means of "Cold Water extraction". Take your fine manicure trim with tricombs and stick em in a large pickle jar filled with 80% ice and fill it to almost the top with water, and shake vigerously for 15-25 minutes (kind of tiring)! Decant all the H20 leaving only the matter resting on the bottem of the jar with some H20, let remains dry and you have youself there some superior ass hash.
This method seperates all the plant matter which floats to top in the water from the THC tricomes which settle at the bottem from being more dense then water.
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#16
 2003-08-30, 17:52
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Wicked_Rain 
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Re: Loperamide (immodium)--->Demerol
quote:Originally posted by 0.S. Sparkel:
yeah finger hash is badass. I fucken can make a 7+ grams just from triming (w/ scissors) like in 6 hours (bomb Humboldt outdoor)!
My favorite type of hash is issolated by means of "Cold Water extraction". Take your fine manicure trim with tricombs and stick em in a large pickle jar filled with 80% ice and fill it to almost the top with water, and shake vigerously for 15-25 minutes (kind of tiring)! Decant all the H20 leaving only the matter resting on the bottem of the jar with some H20, let remains dry and you have youself there some superior ass hash.
This method seperates all the plant matter which floats to top in the water from the THC tricomes which settle at the bottem from being more dense then water.
that method works killer OS. check out this site: http://www.bubblebag.com/main.php
i thinkyou will like it alot. it takes that method to the next level. click on instructions on the left and see it complete with pics.
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#17
 2003-08-30, 17:55
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0.S. Sparkel 
Regular
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Re: Loperamide (immodium)--->Demerol
Yeah a lot of my buddys rock these bubble bags. No they kick some SERIOUS ass!
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#18
 2003-08-30, 17:58
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Wicked_Rain 
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Re: Loperamide (immodium)--->Demerol
agreed!!!
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#19
 2003-08-30, 17:58
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0.S. Sparkel 
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Re: Loperamide (immodium)--->Demerol
Wait, just checked out the site, hmmmmm, can these be applied to ummmmm other types of extractions.
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#20
 2003-08-30, 18:10
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Wicked_Rain 
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Re: Loperamide (immodium)--->Demerol
quote:Originally posted by 0.S. Sparkel:
Wait, just checked out the site, hmmmmm, can these be applied to ummmmm other types of extractions.
dunno but im willin to listen to theories or ideas. we should stop stompin on JA`s thread here since we are off topic. if you come up with an idea or wanna post the bags and ask others for ideas prolly should start a new thread OS. sorry JA
[This message has been edited by Wicked_Rain (edited 08-30-2003).]
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#21
 2003-08-30, 21:15
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J. A. Seed 
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Re: Loperamide (immodium)--->Demerol
you can talk about whatever the fuck you want. Conversations drift and only a stalinist neo fascist would try to stop that. Anyway dont use acetone to make hash as it dissolves chlorophyll as well as THC. Use diethyl ether it makes for some pretty pure hash
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#22
 2003-08-30, 22:32
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kman 
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Re: Loperamide (immodium)--->Demerol
Humboldt rules, dude!
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#23
 2003-08-31, 07:05
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jerky 
Regular
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Re: Loperamide (immodium)--->Demerol
O.S. SPARKEL
Hey dont know if this helps you at all but I saw your mention of Oxycontin. Anyway Im majoritively just a pill popper due to one realy fucked up back. Nothin better than being 23 years old and have degenerative disc disease so Ive turned very tolerant to pain meds. The bills have got so much crap in them now, cellulose and whatever for a less abusable timerelease tablet so most my friends chew them up. I find that crushing them and then adding to very hot h20 they will dissolve and leave the cellulose floating on top.I filter once and then our more hot h20 over the junk in the filter. I then place in an ice bath and refilter again. The final cold filter will remove the acetominophen(sp). I do the with 6 pills with Oxycontin 40mg and only use maybe 2 ounces of water to disolve them so its very concentrated. ANYWAY to cut to the point let me know if you find a way to convert these to crystaline form so its more portable. I may have misread your post but I think this is what you were curious about also.
Thanks
Jerkoli
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#24
 2003-08-31, 20:21
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J. A. Seed 
Regular
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Re: Loperamide (immodium)--->Demerol
Apparently Loperamide can be made to cross the blood brain barrier by combining it with nanoparticles. When i learn more about this ill post what i know
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#25
 2003-08-31, 21:06
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tReePHrOg 
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Re: Loperamide (immodium)--->Demerol
just load up your pipe with some immodium and light, you gomers.
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#26
 2003-09-01, 02:23
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46method 
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Re: Loperamide (immodium)--->Demerol
Wicked, damn if the roads haven't run parrell. The girls r my thing 1st and foremost even before dreaming. this is 2nd yr having a sifter and hash press. got 31/2# of leaf and term buds drying right now. last night ole ladie said ya going to have to something bout that smell coming from the basement. LOL hell harvest ain't for another month and half outdoors bout every 12 weeks in. got 96 gils out/12 in.. in is all clones from "wkykiller", swims on variety that is bout 12 yr in the making.
Damn get swim to talk bout the girls and blab,blab.
Sorry guys!
LATER !!!! !!!!!!
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#27
 2003-09-01, 02:51
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0.S. Sparkel 
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Re: Loperamide (immodium)--->Demerol
when is harvest in Alaska?
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#28
 2003-09-01, 03:31
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em de em aye 
Regular
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Re: Loperamide (immodium)--->Demerol
SO........this is totally off topic but is their any way to make loperamide penatrate the blood brain barrier?
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#29
 2003-09-01, 04:38
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J. A. Seed 
Regular
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Re: Loperamide (immodium)--->Demerol
Yes if you supersaturate with P-450 cytochrome inhibitors (ie. Grapefruit juice or equivalent) 45 min before dosing up 60-100 mgs.
That or you can combine the Loperamide with calcium oxide nano particles in a liquid matrix preferably non polar (olive oil) as Loperamide is not water soluble
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#30
 2003-09-01, 18:38
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Wicked_Rain 
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Re: Loperamide (immodium)--->Demerol
quote:Originally posted by 0.S. Sparkel:
when is harvest in Alaska?
8 weeks after you turn the 1000 watt high pressure sodium bulbs to 12 hours lol
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