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Laboratory Tips Safety proceedures, test reagents, drilling rubber stoppers, bending glass tubes, etc. Contributed to by chemists.

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  #1   Add DarkStarDMT to your ignore list  
Old 2003-07-04, 22:56
DarkStarDMT DarkStarDMT is offline
 
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forgive the newbie (to this end of everything).....SWIM want to know if he has pills that are 25 mg ephedrine and 200 mg guanefesin, is there a method to seperate the two? He has asthma but is allergic to guan.....again, SWIM is a newbie please help, kindly.
  #2   Add pikk to your ignore list  
Old 2003-07-05, 08:11
pikk pikk is offline
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guffy is not souble in pet either. but eph is .
  #3   Add KraKleBack KinG to your ignore list  
Old 2003-07-05, 11:41
KraKleBack KinG KraKleBack KinG is offline
 
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good question.. never bothered with those 25mg e + 200mg guf. pills (mini-thins, right?) / assumed it would be difficult to seperate. so, a pet. ether soak leaves behind guff.?

[This message has been edited by KraKleBack KinG (edited 07-05-2003).]
  #4   Add pikk to your ignore list  
Old 2003-07-05, 19:20
pikk pikk is offline
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Monograph number: 4582

Title: Guaifenesin

CAS Registry number: [93-14-1]

CA name(s): 3-(2-Methoxyphenoxy)-1,2-propanediol;

Additional name(s): glycerol mono(2-methoxyphenyl) ether; glycerol .alpha.-(2-methoxyphenyl) ether; guaiacyl glyceryl ether; glyceryl guaiacyl ether; glycerol guaiacolate; .alpha.-glyceryl guaiacol ether; o- methoxyphenyl glyceryl ether; 1,2-dihydroxy-3-(2-methoxyphenoxy)propane; guaiacol glyceryl ether; guaiphenesin; guaiacuran;

Trade names(s): Actifed-C (Burroughs Wellcome); Calmipan; Colrex Expectorant (Rowell); Equicol (Burns-Bio); Glycodex (Burns-Bio); Guaiamar; Guayanesin; Miocaina; Myocaine; Myoscain; Oresol; Oreson; Relaxil G; Reorganin; Respenyl; Resyl (Ciba); Robitussin (Robins); Sirotol (Stada); Tenntuss; Tulyn.

Drug code(s): MY-301; XL-90;

Molecular formula: C10H14O4

Molecular weight: 198.22

Composition: C 60.59%, H 7.12%, O 32.29%.

Literature references: Centrally acting muscle relaxant with expectorant properties. Prepn: Marle, J. Chem. Soc. 101, 305 (1912); Yale et al., J. Am. Chem. Soc. 72, 3710 (1950); Roviralta, Astoul, Span. pat. 212,920 (1954), C.A. 49, 8332b (1955). Prepn from 2-methoxyphenol and glycidol: W. Merk et al., Ger. pat. 3,106,995 corresp to U.S. pat. 4,390,732 (1982, 1983 to Degussa AG). GLC determn in blood: W. R. Maynard, R. B. Bruce, J. Pharm. Sci. 59, 1346 (1970). Clinical use in chronic respiratory disease: D. G. Workman et al., Curr. Ther. Res. 7, 665 (1965). Clinical efficacy as antitussive: J. J. Kuhn et al., Chest 82, 713 (1982). Pharmacokinetics and cardiopulmonary effects in horses: J. A. E. Hubbell et al., Am. J. Vet. Res. 41, 1751 (1980). Use in equine anesthesia: J. L. Grandy, W. N. McDonell, J. Am. Vet. Med. Assoc. 176, 619 (1980); G. J. Brouwer, Eq. Vet. J. 17, 133 (1985).

Properties: Minute rhombic prisms from ether, mp 78.5-79 deg. bp19215 deg. Slightly bitter aromatic taste. One gram dissolves in 20 ml water at 25 deg. Much more sol in hot water; freely sol in ethanol; sol in chloroform, glycerol, propylene glycol, DMF; moderately sol in benzene. Practically insol in petr ether.

Melting point: 78.5-79

Boiling point: 215

Derivative: Mixture with theophylline (1:1)

CAS Registry number: [5634-38-8]

Additional name(s): guaithylline,

Trade name(s): Eclabron (U.S. Ethicals)

THERAP CAT: Expectorant; guaithylline also as bronchodilator.

THERAP CAT (VET): Expectorant; muscle relaxant.

============================================

so it is like this an a/b with good naptha works well against guffy. but what else is in those pills ?

no a soak in a non polar wont do anything kbk use a a/b with pet either you have to move the sudo in to something that the guffy wont go into

[This message has been edited by pikk (edited 07-05-2003).]

[This message has been edited by pikk (edited 07-05-2003).]
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