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Better Living Through Chemistry Discussions of any and all sorts of mind-warping chemicals, pills, booze, mind machines, trippy stuff, current street prices, importing pharmaceuticals, smart drugs, nutrients, herbs, and altered states. Please try to keep your conversations "theoretical" in nature, since this is an open conference.

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 #1 
Old 2003-08-11, 06:04
151 151 is offline
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Default Serotonin Syndrome?

Okay here is my question...

I have been taking Zoloft, an SSRI, for about 6 months now while also using some other substances. I frequently use alcohol, DXM, weed, opium, vicodin, codiene, with occasional coke and shrooms. I have read though that SSRI's can interact with a number of different drugs that can trigger something called Serotonin Syndrome in the brain which can result in death. Can somebody explain to me which drugs could cause this? I don't really need Zoloft as I have noticed no difference after taking it, I just take it to satisfy my parents. Any thoughts or advice? Thanks.
 #2 
Old 2003-08-11, 06:12
I_Tweak_Too I_Tweak_Too is offline
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Default Re: Serotonin Syndrome?

quote:Originally posted by 151:

Okay here is my question...

I have been taking Zoloft, an SSRI, for about 6 months now while also using some other substances. I frequently use alcohol, DXM, weed, opium, vicodin, codiene, with occasional coke and shrooms. I have read though that SSRI's can interact with a number of different drugs that can trigger something called Serotonin Syndrome in the brain which can result in death. Can somebody explain to me which drugs could cause this? I don't really need Zoloft as I have noticed no difference after taking it, I just take it to satisfy my parents. Any thoughts or advice? Thanks.

i know that dxm could definately cause it. heres a link.

http://third-plateau.org/faq/dxm_side_effects.shtml#toc.6.2.9



yummm knowledge.
 #3 
Old 2003-08-11, 08:35
Fragoholic Fragoholic is offline
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Default Re: Serotonin Syndrome?

Out of those i think dxm is the only one you should worry about.
 #4 
Old 2003-08-11, 12:24
Zcon10 Zcon10 is offline
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Default Re: Serotonin Syndrome?

yeah the dxm is the only real shit you got to worry about.
 #5 
Old 2003-08-11, 17:28
reallystupidstuff reallystupidstuff is offline
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Default Re: Serotonin Syndrome?

i think ecstasy can. so IF you get offered it, be forewarned
 #6 
Old 2003-08-11, 19:57
Synthorcist Synthorcist is offline
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Default Re: Serotonin Syndrome?

Serotonin syndrome can be caricacterised by the metallic taste in the mouth. This is 5-HIAA (5-hydroxyindyleacetic acid. sp?) which is the final product of serotonin metabolism.

There are plenty of 5-HT2b receptors in the lining of the gut...

Synth
 #7 
Old 2003-08-12, 00:11
Harry Pot head1 Harry Pot head1 is offline
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Default Re: Serotonin Syndrome?

quote:Originally posted by reallystupidstuff:

i think ecstasy can. so IF you get offered it, be forewarned

yes xTc can cause it i read it on a site...www.erowid.org and dxm should be the only thing becides the xTc you should worry about
 #8 
Old 2003-08-12, 01:27
kronikus kronikus is offline
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Default Re: Serotonin Syndrome?

While not a risk for causing seratonin syndrome, I would advise against eating mushrooms (or any hallucinagen) while undergoing treatment for depression (especially if using anti-depressants).
 
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